HIV & AIDS
Study finds link between HIV treatment and neuronal degeneration
Antiretroviral drugs have been life-changing therapies for HIV patients, but they can have significant side effects.
Dec 16, 2016
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News tagged with amyloid precursor protein
Cardiology
New heart imaging test identifies improved outcomes in patients with amyloidosis
Researchers at Boston Medical Center (BMC) have reported that a new heart imaging test can determine whether cardiac amyloidosis patients are expected to survive after a stem cell transplant. They accomplished this by analyzing ...
Dec 12, 2016
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Alzheimer's disease & dementia
Dysfunction in neuronal transport mechanism linked to Alzheimer's disease
Researchers at University of California San Diego School of Medicine have confirmed that mutation-caused dysfunction in a process cells use to transport molecules within the cell plays a previously suspected but underappreciated ...
Oct 12, 2016
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1
Alzheimer's disease & dementia
Poison in the brain
Spherical structures in the nucleus of nerve cells, so-called nuclear spheres, are suspected to trigger Alzheimer's disease. A team headed by Dr Thorsten Müller from the research group Cell Signaling in Neurodegeneration ...
Sep 15, 2016
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Alzheimer's disease & dementia
Trial drug shows 'impressive' Alzheimer's action: study
An experimental drug cleared protein buildup in the brains of people with mild Alzheimer's disease and slowed their mental decline, the results of a preliminary trial showed Wednesday.
Aug 31, 2016
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Alzheimer's disease & dementia
Elevating brain protein allays symptoms of Alzheimer's and improves memory
Boosting levels of a specific protein in the brain alleviates hallmark features of Alzheimer's disease in a mouse model of the disorder, according to new research published online August 25, 2016 in Scientific Reports.
Aug 25, 2016
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295
Alzheimer's disease & dementia
Researchers use imaging technique to predict dementia status in adults with down syndrome
Researchers at the University of Kentucky Sanders-Brown Center on Aging found that magnetic resonance spectroscopy (MRS), a noninvasive imaging technique, might help distinguish between people with Down syndrome who have ...
Aug 10, 2016
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Medical research
Human amyloid-beta acts as natural antibiotic in the brains of animal models
A new study from Massachusetts General Hospital (MGH) investigators provides additional evidence that amyloid-beta protein - which is deposited in the form of beta-amyloid plaques in the brains of patients with Alzheimer's ...
May 25, 2016
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301
Alzheimer's disease & dementia
Dysfunctional endosomes are early sign of neurodegeneration
Writing in the April 11 issue of the Journal of Clinical Investigation, researchers at University of California, San Diego School of Medicine say abnormalities in a protein that helps transport and sort materials inside cells ...
Apr 11, 2016
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Alzheimer's disease & dementia
Researchers work to block harmful behavior of key Alzheimer's enzyme
Enzymes rarely have one job. So, attempts to shut down the enzyme that causes the hallmarks of Alzheimer's disease often mean side effects, because these therapies prevent the enzyme from carrying out many other functions. ...
Feb 25, 2016
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