Amyloid plaques—protein clumps that are one of the hallmarks of Alzheimer's disease—occur at roughly the same level in the brains of people with Down syndrome who have Alzheimer's as they do in people with forms of hereditary, ...
Dec 13, 2022
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Around 80% of people with Down syndrome develop Alzheimer's disease, often when they are between 40 and 50 years old. A study led by Lund University in Sweden has shown that a simple blood test can detect Alzheimer's disease ...
Aug 24, 2022
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Lamivudine, a commonly-used antiretroviral drug for treating HIV, improves cognition in a mouse model of Down syndrome, according to the findings of a joint new study by researchers at the Centre for Genomic Regulation (CRG) ...
Jun 28, 2022
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Identifying genetic risk factors for Alzheimer's disease is essential if we are to improve our understanding and treatment of it. Progress in human genome analysis along with genome-wide association studies are now leading ...
Apr 4, 2022
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Researchers have identified amyloid beta (Aβ) detected in blood to originate from peripheral tissues, and that the peptide acts on pancreaticβ-cells to suppress insulin secretion, thereby regulating blood glucose levels. ...
Mar 15, 2022
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Researchers from the Université Laval Faculty of Medicine and CHU de Québec–Université Laval Research Center have successfully edited the genome of human cells grown in vitro to introduce a mutation providing protection ...
Feb 10, 2022
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New research published today in Alzheimer's & Dementia, the journal of the Alzheimer's Association could explain why neurons fail to communicate effectively in people with Alzheimer's disease (AD). The study conducted by ...
Jan 25, 2022
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Alzheimer's disease (AD) is a progressive neurological disease that causes impairments in memory and cognition. AD is believed to result from the deposition of protein "plaques" consisting of amyloid beta (Aβ) proteins sequentially ...
Jan 7, 2022
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Drug hunters hoping to prevent or delay the onset of Alzheimer's disease take note—a new mouse model developed at RIKEN offers a powerful platform for evaluating potential therapies designed to combat the neurodegenerative ...
Dec 1, 2021
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Down syndrome is mostly known for the learning disabilities it causes, but patients typically suffer from a wide number of ailments. One is the early onset of Alzheimer's disease. Using iPS cells from Down syndrome patients, ...
Sep 1, 2021
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