Genetics

Mutations in noncoding DNA are found to protect the brain from ALS

Genetic mutations linked to a disease often spell bad news. Mutations in over 25 genes, for example, are associated with amyotrophic lateral sclerosis, or ALS, and they all increase the risk of developing this incurable disorder. ...

Medications

FDA panel narrowly sides against experimental ALS drug

Federal health advisers on Wednesday narrowly ruled against an experimental drug for the debilitating illness known as Lou Gehrig's disease, a potential setback for patient groups who have lobbied for the medication's approval.

Medications

FDA reviewers give thumbs down to new ALS drug

Despite months of intense lobbying by patient advocates, federal health officials on Monday posted a largely negative review of an experimental drug for amyotrophic lateral sclerosis (ALS).

Diseases, Conditions, Syndromes

Researchers identify a potential window for treating ALS

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder that affects as many as 30,000 people in the United States, with 5,000 new cases diagnosed each year. It weakens muscles over time, impacting physical function ...

Diseases, Conditions, Syndromes

Hybrid Assistive Limb improves gait ability in patients with ALS

Amyotrophic lateral sclerosis (ALS) is a fatal progressive neurodegenerative disease that presents with various symptoms, such as muscle weakness, dysphagia, dysarthria, and respiratory failure, leading to death in 3–5 ...

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