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News tagged with analgesics

The brain on drugs: Defining the neural anatomy and physiology of morphine on dopamine neurons

(Medical Xpress) -- Morphine's analgesic properties are as potent as its addictive potential are problematic. The neural pathway for that addiction is typically associated with dopamine (DA) neurons of the ...

Neuroscience created Oct 04, 2011 | popularity 4.8 / 5 (4) | comments 1 | with audio podcast feature

Prescription overdose rate reaches epidemic levels in NYC

The rate of drug overdose from prescription opioids increased seven-fold in New York City over a 16-year period and was concentrated especially among white residents of the city, according to latest research at Columbia University's ...

Medications created Feb 03, 2013 | popularity 3 / 5 (4) | comments 0 | with audio podcast

A new promising approach in the therapy of pain

The treatment of inflammatory pain can be improved by endogenous opioid peptides acting directly in injured tissue. Scientists at the Charité – Universitätsmedizin Berlin and the Université Paris Descartes showed that ...

Medical research created Dec 04, 2012 | popularity 5 / 5 (2) | comments 0

The sensation of cold is shut down by inflammation

(Medical Xpress) -- Research groups at the University of Cambridge and the Instituto de Neurociencias, in Spain, have discovered a new and unexpected mechanism by which cold sensation is regulated, and opens ...

Medical research created Jul 02, 2012 | popularity 5 / 5 (1) | comments 1 | with audio podcast

A promising clinical trial to reduce the severity of autistic disorders

Although this therapy is not curative, it nevertheless reduced the autistic disorders' severity in three-quarters of the children. The researchers have filed a request for authorisation to perform a multi-centre European ...

Psychology & Psychiatry created Dec 12, 2012 | popularity 5 / 5 (1) | comments 0

New research finds cause of morphine side effects

A University of Colorado Boulder-led research team has discovered that two protein receptors in the central nervous system team up to respond to morphine and cause unwanted neuroinflammation, a finding with implications for ...

Medical research created Apr 02, 2012 | popularity 4 / 5 (1) | comments 0 | with audio podcast

Analgesic

An analgesic (also known as a painkiller) is any member of the group of drugs used to relieve pain (achieve analgesia). The word analgesic derives from Greek an- ("without") and algos ("pain").

Analgesic drugs act in various ways on the peripheral and central nervous systems; they include paracetamol (para-acetylaminophenol, also known in the US as acetaminophen), the non-steroidal anti-inflammatory drugs (NSAIDs) such as the salicylates, and opioid drugs such as morphine and opium. They are distinct from anesthetics, which reversibly eliminate sensation.

In choosing analgesics, the severity and response to other medication determines the choice of agent; the WHO pain ladder, originally developed in cancer-related pain, is widely applied to find suitable drugs in a stepwise manner. The analgesic choice is also determined by the type of pain: for neuropathic pain, traditional analgesics are less effective, and there is often benefit from classes of drugs that are not normally considered analgesics, such as tricyclic antidepressants and anticonvulsants.

For more information about Analgesic, read the full article at Wikipedia.
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