Research by scientists at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) has demonstrated that the on-target molecular and cellular effects of medicines used to modulate the formation of new blood vessels ...
May 31, 2023
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Scientists of the National Center for Cardiovascular Research (CNIC) led by Rui Benedito have discovered a cellular and molecular mechanism that can be exploited to induce productive and sustained angiogenesis in tissues ...
May 1, 2019
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Putting mice on a diet containing low amounts of the essential amino acid methionine triggered the formation of new blood vessels in skeletal muscle, according to a new study from Harvard T.H. Chan School of Public Health. ...
Mar 22, 2018
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Newly published UC Davis research characterizing specific mechanisms involved in blocking angiogenesis, or the formation new blood vessels, has the potential to block cancer growth and target other diseases, researchers said ...
Apr 25, 2017
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In a study conducted by Duke-NUS Medical School (Duke-NUS) and the National Heart Centre Singapore (NHCS), researchers discovered a new gene that controls blood vessel formation. This work presents a possible new drug target ...
Jul 8, 2016
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Rice University researchers have built a simulation to show how cancerous tumors manipulate blood-vessel growth for their own benefit.
Jul 8, 2015
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Sometimes a full-on assault isn't the best approach when dealing with a powerful enemy. A more effective approach, in the long run, may be to target the support system replenishing the supplies that keep your foe strong and ...
Apr 25, 2014
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A team of scientists, led by Napoleone Ferrara, MD, has shown for the first time that a signaling protein involved in inflammation also promotes tumor resistance to anti-angiogenic therapy.
Aug 5, 2013
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(Medical Xpress) -- Stem cells often used in reconstructive surgery following mastectomies and other cancer-removal treatments may pose a danger: Cornell biomedical scientists have discovered that these cells, in contact ...
Jun 5, 2012
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Scientists identify in the journal Nature a new molecular pathway used to suppress blood vessel branching in the developing retina – a finding with potential therapeutic value for fighting diseases of the retina and ...
May 29, 2011
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Angiogenesis is the physiological process involving the growth of new blood vessels from pre-existing vessels. Though there has been some debate over terminology, vasculogenesis is the term used for spontaneous blood-vessel formation, and intussusception is the term for the formation of new blood vessels by the splitting of exisiting ones.
Angiogenesis is a normal and vital process in growth and development, as well as in wound healing and in granulation tissue. However, it is also a fundamental step in the transition of tumors from a dormant state to a malignant one, leading to the use of angiogenesis inhibitors. The identification of an angiogenic diffusible factor derived from tumors was made initially by Greenblatt and Shubik in 1968.
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