Genetics

Neurodegeneration can be studied long before symptoms arise

Many changes take place in the brain long before symptoms appear. This has been shown in mice in two studies of prion diseases in which the brain gradually deteriorates. The results suggest that changes can be studied extremely ...

Medical research

The unexpected cells helping to shape young brains

When the brain first wires itself up in early development, it creates more connections than it actually needs. Some of these connections, or synapses, will transmit critical signals as young animals begin to sense their surroundings. ...

Oncology & Cancer

A window into the changing tumor microenvironment

Researchers led by Ludwig Lausanne's Anoek Zomer, Davide Croci and Johanna Joyce described in a June publication in iScience their development of a multimodal imaging platform to explore, over extended periods, the changing ...

Medical research

When macrophage digestion goes wrong

The exchange of gases between the air we breathe and our blood takes place via alveoli—tiny air sacs in our lungs. For this process to run smoothly, the epithelial cells of the alveoli produce a substance called "surfactant" ...

Medical research

New antiviral therapy may block COVID-19 transmission

By the time you test positive for COVID-19, the SARS-CoV-2 virus has already taken up residence in your respiratory system. With each breath, you expel invisible viral particles into the air—a process known as viral shedding. ...

Genetics

Researchers develop gene therapy for rare ciliopathy

Researchers from the National Eye Institute (NEI) have developed a gene therapy that rescues cilia defects in retinal cells affected by a type of Leber congenital amaurosis (LCA), a disease that causes blindness in early ...

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