Oncology & Cancer

Critical oncology trial data remains hidden

Despite a commitment from the pharmaceutical industry in 2014 to improve data transparency, more than half of the clinical trials that led to the United States Food and Drug Administration approving anticancer medicines over ...

Biomedical technology

Plug-and-play organ-on-a-chip can be customized to the patient

Engineered tissues have become a critical component for modeling diseases and testing the efficacy and safety of drugs in a human context. A major challenge for researchers has been how to model body functions and systemic ...

Medications

Treating tough tumors by exploiting their iron 'addiction'

Researchers at the University of California, San Francisco, have successfully leveraged an FDA-approved drug to halt growth of tumors driven by mutations in the RAS gene, which are famously difficult to treat and account ...

Medications

Simplified antibiotic may set the stage for antitumor treatments

Garden soil houses a variety of bacteria and their natural byproducts—including one that may help halt tumor growth. Lankacidins are molecules that can be isolated from Strepomyces rochei, a common bacterium in soil. In ...

Medications

Cancer therapy using on-site synthesis of anticancer drugs

An international research group at the RIKEN Cluster for Pioneering Research (CPR) has successfully treated cancer in mice using metal catalysts that assemble anticancer drugs together inside the body. Published in the scientific ...

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