News tagged with antisense oligonucleotide
Phase 1 ALS trial is first to test antisense treatment of neurodegenerative disease
The initial clinical trial of a novel approach to treating amyotrophic lateral sclerosis (ALS) – blocking production of a mutant protein that causes an inherited form of the progressive neurodegererative disease – may ...
Neuroscience
Apr 03, 2013 |
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Fighting fat with fat: Stem cell discovery identifies potential obesity treatment
Ottawa scientists have discovered a trigger that turns muscle stem cells into brown fat, a form of good fat that could play a critical role in the fight against obesity. The findings from Dr. Michael Rudnicki's ...
Medical research
Feb 05, 2013 |
4.3 / 5 (8) |
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New design guidelines simplify development of targeted therapies for muscular dystrophy and other diseases
The dystrophin protein offers critical support to muscle fibers. Mutations affecting dystrophin's expression cause the muscle-wasting disease muscular dystrophy. In Duchenne muscular dystrophy (DMD), these ...
Genetics
Jan 30, 2013 |
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Antisense oligonucleotides make sense in myotonic dystrophy
Antisense oligonucleotides – short segments of genetic material designed to target specific areas of a gene or chromosome – that activated an enzyme to "chew up" toxic RNA (ribonucleic acid) could point the way ...
Genetics
Feb 27, 2012 |
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