Epilepsy, where patients suffer from unexpected seizures, affects roughly 1% of the population. These seizures often involve repetitive and excessive neuronal firing, and the trigger behind this still poorly understood.
Apr 19, 2024
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Astrocytes, as vital cells in the central nervous system, are crucial for brain health and function. Recent research shows that they influence higher cognitive functions and behaviors by regulating local neuronal activity.
Apr 22, 2024
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In a joint effort with RIKEN BioResource Research Center and Mitsubishi Tanabe Pharma Corporation, a team of researchers led by Dr. Haruhisa Inoue (Professor, Department of Cell Growth and Differentiation, CiRA) improved ...
Apr 16, 2024
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Astrocytes (etymology: astron gk. star, cyte gk. cell), also known collectively as astroglia, are characteristic star-shaped glial cells in the brain and spinal cord. They perform many functions, including biochemical support of endothelial cells that form the blood–brain barrier, provision of nutrients to the nervous tissue, maintenance of extracellular ion balance, and a role in the repair and scarring process of the brain and spinal cord following traumatic injuries.
Research since the mid-1990s has shown that astrocytes propagate intercellular Ca2+ waves over long distances in response to stimulation, and, similar to neurons, release transmitters (called gliotransmitters) in a Ca2+-dependent manner. Data suggest that astrocytes also signal to neurons through Ca2+-dependent release of glutamate. Such discoveries have made astrocytes an important area of research within the field of neuroscience.
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