News tagged with atorvastatin
Statins plus exercise best at lowering cholesterol, study finds
(HealthDay)—People who exercise along with taking statins to lower their high cholesterol levels can dramatically reduce their risk of dying, a large new study suggests.
Cardiology
Nov 28, 2012 |
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Statins may help prevent irregular heartbeat in elderly
(HealthDay) -- The widely used class of cholesterol-lowering medications known as statins may help elderly patients with high blood pressure avoid developing atrial fibrillation, a heart rhythm abnormality ...
Cardiology
May 10, 2012 |
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Statin alternative looks promising in early trials
(HealthDay) -- Administration of REGN727, a monoclonal antibody to proprotein convertase subtilisin/kexin 9 (PCSK9), significantly reduces low-density lipoprotein (LDL) cholesterol levels, according to the ...
Cardiology
Mar 22, 2012 |
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Risk of new-onset diabetes varies with different statins
(HealthDay)—Different types and doses of statins seem to correlate with distinct risks of developing new-onset diabetes mellitus (DM), according to a meta-analysis published in the April 15 issue of The Am ...
Cancer
Apr 11, 2013 |
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Different drug combinations work best for prevention versus treatment of colorectal tumors
Colorectal cancer is the second leading cause of cancer-related deaths in the United States. Once colorectal cancer has spread to other parts of the body, only 11 percent of patients will survive five years from the date ...
Cancer
Apr 07, 2013 |
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Shopping around brings steep prescription drug savings, report finds
(HealthDay News) —Prescription drug prices at U.S. pharmacies can vary widely, and failing to shop around could result in people overpaying by as much as $100 or more a month on average, depending on the ...
Medications
Mar 28, 2013 |
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High potency statins pose significantly higher risk of kidney injury than low potency, say experts
Patients taking high potency statins for high blood pressure are at a 34% higher risk of being hospitalised for acute kidney injury (AKI), compared with those taking low potency statins, a paper published today in BMJ sugges ...
Cardiology
Mar 19, 2013 |
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Drug protects against kidney injury from imaging dye in ACS patients
High doses of a popular cholesterol-lowering drug significantly reduced the rate of acute kidney injury caused by dye used in imaging in acute coronary syndrome patients who underwent a coronary procedure, according to research ...
Cardiology
Mar 11, 2013 |
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Drugmaker Ranbaxy halts generic Lipitor production
Problem-plagued Ranbaxy Pharmaceuticals Inc. has halted production of generic cholesterol drug Lipitor while it investigates how tiny glass particles got into the ingredients used for dozens of batches of the drug that were ...
Medications
Nov 30, 2012 |
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Ranbaxy recalls generic Lipitor doses
(AP)—Ranbaxy Pharmaceuticals Inc. has recalled dozens of lots of its generic version of cholesterol drug Lipitor because some may contain tiny glass particles, the latest in a string of manufacturing deficiencies that once ...
Medications
Nov 23, 2012 |
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Greater drop in LDL seen with atorvastatin plus PCSK9 antibody
(HealthDay)—Addition of the fully human serum proprotein convertase subtilisin/kexin 9 monoclonal antibody, SAR236553, to atorvastatin is associated with greater reductions in low-density lipoprotein (LDL) ...
Medical research
Nov 02, 2012 |
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Study finds statin costs 400 percent higher in US compared to UK
In the United States, the cost paid for statins (drugs to lower cholesterol) in people under the age of 65 who have private insurance is approximately 400 percent higher than comparable costs paid by the government in the ...
Medications
Jan 05, 2012 |
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With new generic rivals, Lipitor's sales halved
Sales of cholesterol blockbuster Lipitor plunged by half barely a week after the world's top-selling drug got its first U.S. generic competition, new data show.
Medications
Dec 20, 2011 |
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Pfizer's blockbuster drug Lipitor goes generic
Pfizer's patent on the best-selling drug of all-time, the cholesterol-lowering medication Lipitor, expired on Wednesday, opening the path to generic competitors for America's most popular medication.
Medications
Nov 30, 2011 |
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Two statin drugs similarly effective in reversing coronary heart disease
Maximum doses of Crestor (rosuvastatin) or Lipitor (atorvastatin) are similarly effective in reversing the buildup of cholesterol plaques in the coronary artery walls (atherosclerosis) after 24 months of treatment, according ...
Cardiology
Nov 15, 2011 |
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Atorvastatin
Atorvastatin (INN) ( /əˌtɔrvəˈstætən/), sold by Pfizer under the trade name Lipitor, is a member of the drug class known as statins, used for lowering blood cholesterol. It also stabilizes plaque and prevents strokes through anti-inflammatory and other mechanisms. Like all statins, atorvastatin works by inhibiting HMG-CoA reductase, an enzyme found in liver tissue that plays a key role in production of cholesterol in the body.
Atorvastatin was first synthesized in 1985 by Bruce Roth while working at Parke-Davis Warner-Lambert Company (now Pfizer). With 2008 sales of US$12.4 billion, Lipitor was the top-selling branded pharmaceutical in the world. U.S. patent protection was scheduled to expire in June 2011. However, Pfizer made an agreement with Ranbaxy Laboratories to delay the generic launch in the U.S. until November 30, 2011.
For more information about Atorvastatin, read the full article at
Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.
