A team of medical researchers affiliated with a host of institutions in the U.S. has used base editing to restore the natural production of the SMN protein in mice, effectively curing spinal muscular atrophy (SMA) in the ...
Scientists in Cambridge and Berlin have used a form of gene therapy to increase levels of the so-called "cold shock protein" in the brains of mice, protecting them against the potentially devastating impact of prion disease.
Mar 24, 2023
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Columbia researchers have discovered how a genetic defect leads to spinal muscular atrophy (SMA), a critical piece of information about the disease that neurologists have been seeking for decades.
Mar 22, 2023
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Researchers at The Ohio State University have fabricated the first wearable sensor designed to detect and monitor muscle atrophy.
Mar 17, 2023
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Sarcopenia is the decline of skeletal muscle mass with age, leading to loss of muscle strength (to move objects, shake hands etc.) and performance (walking and making other routine movements effectively). It involves chronic ...
Mar 2, 2023
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Living organisms have a knack for persisting in the face of challenges. For instance, when genes malfunction, organisms may be able to compensate by activating redundant genes with similar functions, called paralogs.
Feb 21, 2023
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Alzheimer's disease is the most common form of dementia, accounting for 60% to 80% of dementia cases, according to the Alzheimer's Association. While current research suggests alcohol use disorder is a risk factor in Alzheimer's ...
Feb 17, 2023
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Professor Megumu K. Saito and his colleagues have revealed that SMN, a protein involved in spinal muscular atrophy (SMA), promotes the functional maturation of mitochondria by regulating miRNA expression along with MYOD1 ...
Feb 17, 2023
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Scientists from CSIRO, Australia's national science agency, in partnership with Queensland University of Technology, have used artificial intelligence to develop a world-first benchmark for measuring brain atrophy—or thinning—in ...
Feb 1, 2023
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Newborn screening (NBS) for spinal muscular atrophy (SMA), when combined with early treatment, results in better movement ability in affected children, including the ability to walk, when compared to children who are diagnosed ...
Jan 18, 2023
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