Neuroscience
White matter hyperintensity load is associated with premature brain aging
A new research paper titled "White matter hyperintensity load is associated with premature brain aging" has been published in Aging.
Dec 22, 2022
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News tagged with atrophy
Medications
With high costs and similar benefits, use of new neurology drugs is low
A number of new neurologic medications for diseases like multiple sclerosis (MS), Parkinson's disease and migraine have received U.S. Food and Drug Administration (FDA) approval over the past decade. However, with most having ...
Nov 30, 2022
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Medical research
Scientists explore a link between lethal childhood disease and age-related muscle decline
Adopting some of the strategies behind successfully treating the childhood disease spinal muscular atrophy may enable development of therapies to curb the muscle decline that accompanies aging, new research suggests.
Nov 15, 2022
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Sports medicine & Kinesiology
Helping wasting muscles build back better
Muscles waste as a result of not being exercised enough, as happens quickly with a broken limb that has been immobilized in a cast, and more slowly in people reaching an advanced age. Muscle atrophy, how clinicians refer ...
Nov 14, 2022
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Neuroscience
MS clinicians, here's how your patients need you to talk about brain atrophy with them
For people with multiple sclerosis (MS), hearing a doctor tell them they are experiencing brain atrophy—an important, predictive biomarker of MS disease progression—can trigger debilitating fear and anxiety.
Nov 14, 2022
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Genetics
Experts encourage earlier intervention for some infants with spinal muscular atrophy
Spinal muscular atrophy (SMA), the most common form of neurodegenerative disease in childhood, is caused by defects in the SMN1 gene. SMA patients potentially benefit from three recently approved disease-modifying therapies. ...
Nov 7, 2022
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Diseases, Conditions, Syndromes
Gene therapy with AAV serotype 2 capsid variants for improved liver disease treatments
There are numerous severe, difficult-to-treat monogenetic diseases that are caused by a defect in a single gene—also in the liver. These include the blood coagulation disorders hemophilia A or B or the metabolic disease ...
Oct 26, 2022
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Genetics
Exposing the evolutionary weak spots of the human genome
Mutations can be good and bad. Sometimes they help an organism adapt and survive. Other times they are so harmful that an organism can't survive or reproduce. Cold Spring Harbor Laboratory (CSHL) Professor Adam Siepel's team ...
Sep 22, 2022
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Neuroscience
Aerobic exercise training promising for restoring function in individuals with MS-related thalamic atrophy
Thalamic atrophy needs to be considered in clinical studies of the functional abilities of individuals with multiple sclerosis, according to findings reported by a team of experts. The article, "Thalamic atrophy moderates ...
Sep 19, 2022
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Medications
Novartis says two children treated with gene therapy died
Two children who received Zolgensma, a gene therapy produced by Swiss drugmaker Novartis to treat spinal muscular atrophy, have died from liver failure, the company said Friday.
Aug 12, 2022
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