Medical research
COVID-19 cytokine storm: Possible mechanism for the deadly respiratory syndrome
Research into how the SARS-CoV-2 virus induces death is suggesting potential treatments for its most destructive complications.
May 20, 2020
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News tagged with b cell receptor
Oncology & Cancer
New CAR T-cell immunotherapy shows promising results for treating blood cancer patients
Blood cancer patients, especially when they relapse, have a poor prognosis, and generally do not survive very long. The last five years have seen success in treating these patients with Chimeric Antigen Receptor (CAR) T-cells—a ...
Feb 24, 2023
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HIV & AIDS
New HIV vaccine approach targets desirable immune cells
Researchers at Duke University Medical Center, Beth Israel Deaconess Medical Center and Harvard Medical School have demonstrated an approach to HIV vaccine design that uses an altered form of HIV's outer coating or envelope ...
Sep 1, 2011
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Genetics
Researchers link mutations in antibodies to heightened risk of allergic diseases in children
A team of researchers from Stanford University, the University of Cincinnati, Children's Hospital Medical Center and the Garvan Institute of Medical Research has found a link between mutated antibodies and a heightened risk ...
Oncology & Cancer
B cell receptor inhibitor causes chronic lymphocytic leukemia remission
A new, targeted approach to treating chronic lymphocytic leukemia has produced durable remissions in a Phase I/II clinical trial for patients with relapsed or resistant disease, investigators report at the 53rd Annual Meeting ...
Dec 11, 2011
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Oncology & Cancer
Researchers characterize mechanism of action of CAR T cells
The scientific community has made great strides over the past decade in the development of a new class of cancer therapy called immunotherapy, a treatment that activates a patient's own immune system to target cancer cells. ...
Feb 14, 2019
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Diseases, Conditions, Syndromes
Scientists explore using body's 'own' immune cells to target infectious diseases including COVID-19
The engineering of specific virus-targeting receptors onto a patient's own immune cells is now being explored by scientists from Duke-NUS Medical School (Duke-NUS), as a potential therapy for controlling infectious diseases, ...
Apr 21, 2020
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182
Medical research
New study shows how B cells may generate antibodies after vaccination
Steve Reiner, MD, professor of Medicine, and Burton Barnett, a doctoral student in the Reiner lab at the Perelman School of Medicine at the University of Pennsylvania, have shown how immune cells, called B lymphocytes, are ...
Dec 15, 2011
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Neuroscience
Researchers discover potential cause of immunotherapy-related neurotoxicity
New research has uncovered the previously unknown presence of CD19—a B cell molecule targeted by chimeric antigen receptor (CAR) T cell immunotherapy to treat leukemia, lymphoma, and multiple myeloma—in brain cells that ...
Sep 21, 2020
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Oncology & Cancer
Receptor structure reveals new targets for cancer treatment
A molecule known as anaplastic lymphoma kinase (ALK) is a driver of several cancers, including pediatric neuroblastoma, B-cell lymphomas, and myofibroblast tumors. But for years much about this molecule—its role in the ...
Nov 26, 2021
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