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Inhibition of PBEF is a possible therapeutic target for pulmonary hypertension

Inhibition of pre-B Cell Colony-Enhancing Factor (PBEF) could be a potential therapeutic target for pulmonary hypertension (PH), according to a preclinical study in an animal model of PH.

Diseases, Conditions, Syndromes created May 22, 2012 | popularity not rated yet | comments 0

Scientists show how memory B cells stay 'in class' to fight different infections

Scientists at The Scripps Research Institute have made an important discovery about the internal programming of B cells, the immune cells that make antibodies against infections. The finding opens the way for the development ...

Immunology created May 07, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Protein may represent a switch to turn off B cell lymphoma

Researchers studying the molecular signals that drive a specific type of lymphoma have discovered a key biological pathway leading to this type of cancer. Cancerous cells have been described as being "addicted" to certain ...

Cancer created May 07, 2012 | popularity 5 / 5 (1) | comments 0

Gut flora affects maturation of B cells in infants

Infants whose gut is colonised by E. coli bacteria early in life have a higher number of memory B cells in their blood, reveals a study of infants carried out at the Sahlgrenska Academy at the University of Gothenburg, Sweden ...

Immunology created May 07, 2012 | popularity not rated yet | comments 0

Combination of 2 drugs reverses liver tumors

The combination of two inhibitors of protein mTOR stops the growth of primary liver cancer and destroys tumour cells, according to a study by researchers of the Group of Metabolism and Cancer at Bellvitge Biomedical Research ...

Medications created May 02, 2012 | popularity not rated yet | comments 0

Lymphoma therapy could deliver a double punch

B cell lymphomas are a group of cancers of that originate in lymphoid tissue from B cells, the specialized immune cell type that produces antibodies. The development of B cell lymphoma is associated with several known genetic ...

Cancer created Apr 30, 2012 | popularity 5 / 5 (2) | comments 0

Gene signature helps identify risk of relapse in lung cancer patients

A new genetic signature identified by Spanish researchers may provide doctors with robust and objective information about which patients with early stage lung cancer are at low or high risk of relapse following surgery, investigators ...

Cancer created Apr 18, 2012 | popularity 5 / 5 (1) | comments 0

Chemotherapy proves life-saving for some leukemia patients who fail induction therapy

An international study found that bone marrow transplants are not the best option for some young patients with acute lymphoblastic leukemia (ALL) who fail to attain clinical remission after the initial weeks of intense chemotherapy ...

Cancer created Apr 11, 2012 | popularity not rated yet | comments 0

Origin of chronic lymphatic leukaemia: lead discovered

Up until now the causes of the development of chronic lymphatic leukaemia, the most common form of cancer of the blood in Europe, have been unknown. At present a cure is not possible. A research group at the ...

Cancer created Apr 11, 2012 | popularity 5 / 5 (2) | comments 0

Researchers find Epstein Barr-like virus infects and may cause cancer in dogs

More than 90 percent of humans have antibodies to the Epstein Barr virus. Best known for causing mononucleosis, or "the kissing disease," the virus has also been implicated in more serious conditions, including Hodgkin's, ...

Cancer created Mar 12, 2012 | popularity 5 / 5 (2) | comments 0

Antibodies are not required for immunity against some viruses

A new study turns the well established theory that antibodies are required for antiviral immunity upside down and reveals that an unexpected partnership between the specific and non-specific divisions of the immune system ...

Immunology created Mar 01, 2012 | popularity not rated yet | comments 0 | with audio podcast

Modified bone drug kills malaria parasite in mice

A chemically altered osteoporosis drug may be useful in fighting malaria, researchers report in a new study. Unlike similar compounds tested against other parasitic protozoa, the drug readily crosses into ...

Medical research created Feb 27, 2012 | popularity 5 / 5 (4) | comments 1 | with audio podcast

A single protein helps the body keep watch over the Epstein-Barr virus

Some 90 percent of people are exposed to the Epstein Barr virus (EBV) at some point in their life. Even though it is quickly cleared from the body, the virus can linger silently for years in small numbers of infected B cells. ...

Medical research created Feb 17, 2012 | popularity 5 / 5 (1) | comments 1 | with audio podcast

Antibodies to intracellular cancer antigens combined with chemotherapy enhance anti-cancer immunity

An international team of scientists in Japan, Switzerland, and the United States has confirmed that combining chemotherapy and immunotherapy in cancer treatment enhances the immune system's ability to find and eliminate cancer ...

Cancer created Feb 13, 2012 | popularity 5 / 5 (1) | comments 0

Coffee consumption reduces fibrosis risk in those with fatty liver disease

Caffeine consumption has long been associated with decreased risk of liver disease and reduced fibrosis in patients with chronic liver disease. Now, newly published research confirms that coffee caffeine consumption reduces ...

Diseases, Conditions, Syndromes created Feb 02, 2012 | popularity 5 / 5 (1) | comments 0