Decoded: Molecular messages that tell prostate and breast cancers to spread
Cancer cells are wily, well-traveled adversaries, constantly side-stepping treatments to stop their spread. But for the first time, scientists at the University of Michigan have decoded the molecular chatter that ramps certain ...
Cancer
Apr 30, 2013 |
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Could a cancer drug potentially prevent learning disabilities in some kids?
A drug originally developed to stop cancerous tumors may hold the potential to prevent abnormal brain cell growth and learning disabilities in some children, if they can be diagnosed early enough, a new animal ...
Cancer
Aug 29, 2012 |
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Key enzyme plays roles as both friend and foe to cancer
A molecule thought to limit cell proliferation also helps cancer cells survive during initial tumor formation and when the wayward cells spread to other organs in the body, researchers at the University of ...
Medical research
Jun 14, 2012 |
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Research identifies targeted molecular therapy for untreatable NF1 tumors
Researchers conducting a preclinical study in mice successfully used targeted molecular therapy to block mostly untreatable nerve tumors that develop in people with the genetic disorder Neurofibromatosis 1 (NF1).
Cancer
Dec 10, 2012 |
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Two gene mutations drive adrenal cancer
Two different genetic mutations cooperate to induce adrenal cancer, according to a new study from researchers at the University of Michigan Comprehensive Cancer Center and University of Sao Paulo in Brazil.
Cancer
Sep 10, 2012 |
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Scientists make mouse model of human cancer, demonstrate cure
UT Southwestern Medical Center scientists report the first successful blocking of tumor development in a genetic mouse model of an incurable human cancer.
Cancer
Mar 05, 2013 |
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Genomic sequencing identifies mutant 'drivers' of common brain tumor
Large-scale genomic sequencing has revealed two DNA mutations that appear to drive about 15 percent of brain tumors known as meningiomas, a finding that could lead to the first effective drug treatments for the tumors, report ...
Genetics
Jan 22, 2013 |
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Protein that functions in normal breast may also contribute to breast cancer metastasis
The trefoil factor 3 (TFF3) protein protects and maintains the integrity of the epithelial surface in the normal breast. New research has found that while TFF3 protein expression is higher in well-differentiated low grade ...
Cancer
Feb 16, 2012 |
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Different drug combinations work best for prevention versus treatment of colorectal tumors
Colorectal cancer is the second leading cause of cancer-related deaths in the United States. Once colorectal cancer has spread to other parts of the body, only 11 percent of patients will survive five years from the date ...
Cancer
Apr 07, 2013 |
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Study suggests smoking, but not nicotine, reduces risk for rare tumor
New research confirms an association between smoking and a reduced risk for a rare benign tumor near the brain, but the addition of smokeless tobacco to the analysis suggests nicotine is not the protective substance.
Cancer
Apr 23, 2012 |
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Deleting a single gene results in autism-like behavior; immunosuppressant drug prevents symptoms
Deleting a single gene in the cerebellum of mice can cause key autistic-like symptoms, researchers have found. They also discovered that rapamycin, a commonly used immunosuppressant drug, prevented these symptoms.
Genetics
Jul 02, 2012 |
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BPA exposure in pregnant mice changes gene expression of female offspring
Prenatal exposure to bisphenol A, or BPA, a chemical found in many common plastic household items, can cause numerous genes in the uterus to respond differently to estrogen in adulthood, according to a study using a mouse ...
Health
Jun 26, 2012 |
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Denosumab reduces burden of giant-cell tumor of the bone
Treatment with denosumab, a drug targeted against a protein that helps promote bone destruction, decreased the number of tumor giant cells in patients with giant-cell tumor of the bone, and increased new bone formation, according ...
Cancer
Sep 21, 2012 |
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Vitamin D shrinks fibroid tumors in rats
Treatment with vitamin D reduced the size of uterine fibroids in laboratory rats predisposed to developing the benign tumors, reported researchers funded by the National Institutes of Health.
Obstetrics & gynaecology
Mar 01, 2012 |
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Breakthrough in genetics of fibroids
Uterine leiomyomas, also called fibroids, cause a very significant burden to women's health. They are benign tumors that occur in 60% of women by the age of 45 years and cause symptoms such as abdominal pain and discomfort, ...
Medical research
Aug 25, 2011 |
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