News tagged with beta amyloid
New perspective needed for role of major Alzheimer's gene
(Medical Xpress)—Scientists' picture of how a gene strongly linked to Alzheimer's disease harms the brain may have to be revised, researchers at Washington University School of Medicine in St. Louis have found.
Medical research
May 07, 2013 |
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FDA-approved drug rapidly clears amyloid from the brain, reverses Alzheimer's symptoms in mice
Neuroscientists at Case Western Reserve University School of Medicine have made a dramatic breakthrough in their efforts to find a cure for Alzheimer's disease. The researchers' findings, published in the journal Science, show t ...
Neuroscience
Feb 09, 2012 |
4.9 / 5 (73) |
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First study to suggest that the immune system may protect against Alzheimer's changes in humans
Recent work in mice suggested that the immune system is involved in removing beta-amyloid, the main Alzheimer's-causing substance in the brain. Researchers have now shown for the first time that this may apply in humans.
Alzheimer's disease & dementia
May 25, 2012 |
4.5 / 5 (6) |
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Accused of complicity in Alzheimer's, amyloid proteins may be getting a bad rap
Amyloids—clumps of misfolded proteins found in the brains of people with Alzheimer's disease and other neurodegenerative disorders—are the quintessential bad boys of neurobiology. They're thought to muck up the seamless ...
Alzheimer's disease & dementia
Apr 03, 2013 |
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Antioxidant may disrupt Alzheimer's disease process
Alzheimer's disease (AD) is now the sixth leading cause of death among Americans, affecting nearly 1 in 8 people over the age of 65. There is currently no treatment that alters the course of this disease. However, an increasing ...
Alzheimer's disease & dementia
Apr 10, 2012 |
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Mystery ingredient in coffee boosts protection against Alzheimer's disease
A yet unidentified component of coffee interacts with the beverage's caffeine, which could be a surprising reason why daily coffee intake protects against Alzheimer's disease. A new Alzheimer's mouse study by researchers ...
Health
Jun 21, 2011 |
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Bursts of brain activity may protect against Alzheimer's disease
Evidence indicates that the accumulation of amyloid-beta proteins, which form the plaques found in the brains of Alzheimer's patients, is critical for the development of Alzheimer's disease, which impacts 5.4 million Americans. ...
Alzheimer's disease & dementia
Apr 18, 2013 |
4.7 / 5 (3) |
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Study reveals multiple mechanisms may play role in Alzheimer's
(Medical Xpress)—Researchers investigating a known gene risk factor for Alzheimer's disease discovered it is associated with lower levels of beta amyloid—a brain protein involved in Alzheimer's—in cognitively healthy ...
Neuroscience
Oct 02, 2012 |
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Vascular brain injury greater risk factor than amyloid plaques in cognitive aging
Vascular brain injury from conditions such as high blood pressure and stroke are greater risk factors for cognitive impairment among non-demented older people than is the deposition of the amyloid plaques in the brain that ...
Neuroscience
Feb 11, 2013 |
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Less tau reduces seizures and sudden death in severe epilepsy
Deleting or reducing expression of a gene that carries the code for tau, a protein associated with Alzheimer's disease, can prevent seizures in a severe type of epilepsy linked to sudden death, said researchers at Baylor ...
Neuroscience
Jan 22, 2013 |
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Surgical menopause may prime brain for stroke, Alzheimer's
Women who abruptly and prematurely lose estrogen from surgical menopause have a two-fold increase in cognitive decline and dementia.
Neuroscience
Mar 28, 2013 |
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Looking for the anti-Alzheimer's molecule: A new approach to treating a devastating disease
Researchers at Dalhousie University have discovered a new technique using "computer-aided" drug design that may lead to an entirely new approach in the treatment of Alzheimer's disease (AD).
Alzheimer's disease & dementia
Nov 07, 2012 |
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Blocking the effects of amyloid b in Alzheimer's disease
During Alzheimer's disease, 'plaques' of amyloid beta (Ab) and tau protein 'tangles' develop in the brain, leading to the death of brain cells and disruption of chemical signaling between neurons. This leads to loss of memory, ...
Alzheimer's disease & dementia
Jul 30, 2012 |
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Plaque build-up in your brain may be more harmful than having Alzheimer's gene
A new study shows that having a high amount of beta amyloid or "plaques" in the brain associated with Alzheimer's disease may cause steeper memory decline in mentally healthy older people than does having the APOE ɛ4 allele, ...
Neuroscience
Oct 15, 2012 |
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Trial set to see if drug can prevent Alzheimer's
(HealthDay) -- Researchers are preparing to test an experimental drug in people genetically primed to develop Alzheimer's disease.
Alzheimer's disease & dementia
May 16, 2012 |
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Beta amyloid
Amyloid beta (Aβ or Abeta) is a peptide of 39–43 amino acids that appear to be the main constituent of amyloid plaques in the brains of Alzheimer's disease patients. Similar plaques appear in some variants of Lewy body dementia and in inclusion body myositis, a muscle disease. Aβ also forms aggregates coating cerebral blood vessels in cerebral amyloid angiopathy. These plaques are composed of a tangle of regularly ordered fibrillar aggregates called amyloid fibers, a protein fold shared by other peptides such as prions associated with protein misfolding diseases. Research on laboratory rats suggest that the two-molecule, soluble form of the peptide is a causative agent in the development of Alzheimer's and that the two-molecule form is the smallest synaptotoxic species of soluble amyloid beta oligomer
For more information about Beta amyloid, read the full article at
Wikipedia.
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