Obstetrics & gynaecology

Vaginal immune system may hint at prime vaccine timing

Levels of key immune-signaling molecules in the vagina "undergo clear and consistent" fluctuations during the menstrual cycle, a University of Washington Medicine-led team reports in a study published today in the journal ...

Alzheimer's disease & dementia

Researchers identify new model of Alzheimer's as an autoimmune disease

Scientists at the Krembil Brain Institute, part of the University Health Network, have proposed a new mechanistic model (AD2) for Alzheimer's, looking at it not as a brain disease, but as a chronic autoimmune condition that ...

Overweight & Obesity

Insufficient insulin processing leads to obesity

Obesity increases the risk of an imbalance in sugar metabolism and even of diabetes. A research group at the University of Basel has now shown the opposite is true as well: deficits in the body's insulin production contribute ...

Diabetes

SMNDC1 loss induces alpha cells to produce insulin

Beta cells in the pancreas are responsible for producing the vital hormone insulin. In diabetes, these cells are either destroyed or functionally impaired, resulting in elevated blood sugar levels in the body.

Medical research

Multiple sclerosis drug works in a surprising way

Drugs called interferon betas are common treatments for multiple sclerosis (MS), reducing relapses and slowing motor function decline. Interferon beta, a protein known to contain a zinc binding pocket, is thought to reduce ...

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