News tagged with binding site

Related topics: antibodies




'Traffic' in our cells works both for and against us

A mechanism that permits essential substances to enter our cells while at the same time removing from them harmful components also has a "down side." This negative aspect prevents vital drugs, such as anti-cancer drugs, from ...

Medical research created May 01, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Better 'mousetrap' discovered in fruit flies might stop human cancer-driving kinase in its tracks

A seemingly obscure gene in the female fruit fly that is only active in cells that will become eggs has led researchers at the Stowers Institute for Medical Research to the discovery of a atypical protein ...

Cancer created Mar 13, 2013 | popularity 5 / 5 (3) | comments 0 | with audio podcast

From protein signaling to cancer drug development

(Medical Xpress)—Living organ­isms depend on pro­teins for their sur­vival. These large, com­plex mol­e­cules mediate nearly every life func­tion, but when the genes that code for them start to mutate, ...

Cancer created Jan 08, 2013 | popularity 5 / 5 (1) | comments 0

Serendipity points to new potential target and therapy for melanoma

(Medical Xpress)—A University of Colorado Cancer Center study in this month's edition of the Journal of Investigative Dermatology describes a new target and potential treatment for melanoma, the most d ...

Cancer created Dec 20, 2012 | popularity not rated yet | comments 0 | with audio podcast

New findings on glucagon synthesis

Researchers at Karolinska Institutet in Sweden have shown that the cells that produce glucagon are stimulated by the hormone itself. A previous study by the same group demonstrated that this principle also applies to insulin. ...

Medical research created Dec 03, 2012 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Team pinpoints amino acid variation in immune response gene linked with ulcerative colitis

The association between the inflammatory bowel disease ulcerative colitis and a gene that makes certain cell surface proteins has been pinpointed to a variant amino acid in a crucial binding site that profoundly influences ...

Immunology created Dec 15, 2011 | popularity not rated yet | comments 0 | with audio podcast

Researchers determine how antibody recognizes key sugars on HIV surface

HIV is coated in sugars that usually hide the virus from the immune system. Newly published research reveals how one broadly neutralizing HIV antibody actually uses part of the sugary cloak to help bind to the virus. The ...

HIV & AIDS created Nov 23, 2011 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Biologists create anti-HIV antibody that shows increased potency

Using highly potent antibodies isolated from HIV-positive people, researchers have recently begun to identify ways to broadly neutralize the many possible subtypes of HIV. Now, a team led by biologists at ...

HIV & AIDS created Oct 27, 2011 | popularity 5 / 5 (4) | comments 0 | with audio podcast

Key function of mutation in hereditary breast and ovarian cancer gene discovered

It is widely known that mutations in the breast cancer susceptibility 1 (BRCA1) gene significantly increase the chance of developing breast and ovarian cancers, but the mechanisms at play are not fully understood. Now, researchers ...

Genetics created Sep 01, 2011 | popularity not rated yet | comments 0 | with audio podcast

Scientists map route for eliciting HIV-neutralizing antibodies

Researchers have traced in detail how certain powerful HIV neutralizing antibodies evolve, a finding that generates vital clues to guide the design of a preventive HIV vaccine, according to a study appearing in Science Ex ...

HIV & AIDS created Aug 11, 2011 | popularity not rated yet | comments 0 | with audio podcast

Scientists identify broad and potent HIV antibodies that mimic CD4 binding

In a finding that may be good news for scientists developing HIV vaccines and therapies, a team of researchers at The Rockefeller University and the Howard Hughes Medical Institute have found a way to investigate ...

HIV & AIDS created Jul 20, 2011 | popularity not rated yet | comments 0

One drug, many targets: Finding molecular targets of an HIV drug used in cancer therapy

Researchers at the University of California, San Diego and Hunter College of the City University of New York (CUNY) have identified potential human molecular targets of the anti-HIV drug Nelfinavir, which may explain why ...

Medications created Apr 28, 2011 | popularity 5 / 5 (1) | comments 0 | with audio podcast