(Medical Xpress) -- Comparing the DNA from patients at the best and worst extremes of a health condition can reveal genes for resistance and susceptibly. This approach discovered rare variations in the DCTN4 ...
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(Medical Xpress)—Virginia Tech scientists have provided new evidence that biofilms—bacteria that adhere to surfaces and build protective coatings—are at work in the survival of the human pathogen Salmonella.
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Eliminating bacteria's DNA and boosting antimicrobial proteins that already exist may help prevent middle ear infections from reoccurring. These are the findings from a Nationwide Children's Hospital study that examined how ...
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Scientists at Queen's University Belfast have developed a new technique which has the potential to kill off hospital superbugs like Pseudomonas aeruginosa, C. difficile and MRSA.
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(HealthDay) -- The food additive maltodextrin, commonly used in some artificial sweeteners, may worsen Crohn's disease by encouraging the growth of E. coli bacteria in the small intestine, a new study suggests.
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Bacteria such as Staphylococcus aureus, the 'superbug' behind MRSA, can be a major problem for patients who have a medical implant, such as a replacement heart valve or pacemaker.
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(Medical Xpress) -- Researchers at the University of Liverpool are examining the evolution of Pseudomonas aeruginosa over time in the lungs of ten people with cystic fibrosis to understand why it persists ...
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Exposure to cigarette smoke has long been associated with increased frequency of respiratory infections—which are harder to treat in smoke-exposed people than in those who lack such exposures. Now Ritwij Kulkarni of Columbia ...
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(HealthDay)—Pacifiers are universally popular with new parents and their infants, but there's one big problem with them: They can get dirty. Very dirty.
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There's new hope for development of an antibiotic that can put down a lethal bacteria or superbug linked to the deaths of hundreds of hospital patients around the world.
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According to the World Health Organization (WHO), one-third of the world's population is currently infected with tuberculosis bacteria. The bacteria is incredibly resistant to treatment, and despite its prevalence, ...
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A biofilm is an aggregate of microorganisms in which cells adhere to each other on a surface. These adherent cells are frequently embedded within a self-produced matrix of extracellular polymeric substance (EPS). Biofilm EPS, which is also referred to as slime (although not everything described as slime is a biofilm), is a polymeric conglomeration generally composed of extracellular DNA, proteins, and polysaccharides. Biofilms may form on living or non-living surfaces and can be prevalent in natural, industrial and hospital settings. The microbial cells growing in a biofilm are physiologically distinct from planktonic cells of the same organism, which, by contrast, are single-cells that may float or swim in a liquid medium.
Microbes form a biofilm in response to many factors, which may include cellular recognition of specific or non-specific attachment sites on a surface, nutritional cues, or in some cases, by exposure of planktonic cells to sub-inhibitory concentrations of antibiotics. When a cell switches to the biofilm mode of growth, it undergoes a phenotypic shift in behavior in which large suites of genes are differentially regulated.
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