Genetics

Researchers clarify role of blood cell mutations in disease

More than 10% of older adults develop somatic (non-inherited) mutations in blood stem cells that can trigger explosive, clonal expansions of abnormal cells, increasing the risk for blood cancer and cardiovascular disease.

Alzheimer's disease & dementia

Big data analysis powers the fight against Alzheimer's

Alzheimer's disease has always had its puzzles and contradictions. For Pacific Northwest National Laboratory (PNNL) researcher Vladislav Petyuk, whose research on the progressive, age-related disease spans over a decade, ...

Genetics

Sharing variant information to improve diagnosis

A national platform for diagnostic laboratories to share genetic evidence and build consistent interpretations of that information is paving the way for more accurate diagnosis of patient conditions.

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