Key mechanism for a common form of Alzheimer's disease discovered
Scientists from the Icahn School of Medicine at Mount Sinai, in collaboration with researchers from Icelandic Heart Association, Sage Bionetworks, and other institutions, have discovered that a network of genes involved in ...
Alzheimer's disease & dementia
Apr 25, 2013 |
4.6 / 5 (5) |
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Large-scale genetic study defines relationship between primary sclerosing cholangitis and other autoimmune diseases
For the first time, scientists show that a leading cause of liver transplant, primary sclerosing cholangitis (PSC), is a distinct disease from inflammatory bowel disease, opening up new avenues for specific PSC treatments.
Genetics
Apr 21, 2013 |
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Hundreds of alterations and potential drug targets to starve cancer tumors identified
A massive study analyzing gene expression data from 22 tumor types has identified multiple metabolic expression changes associated with cancer. The analysis, conducted by researchers at Columbia University Medical Center, ...
Cancer
Apr 21, 2013 |
5 / 5 (4) |
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Key pathway to stop dangerous, out-of-control inflammation discovered
A potential new strategy to developing new drugs to control inflammation without serious side effects has been found by Georgia State University researchers and international colleagues.
Inflammatory disorders
Apr 09, 2013 |
5 / 5 (4) |
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International consortium builds 'Google Map' of human metabolism
Building on earlier pioneering work by researchers at the University of California, San Diego, an international consortium of university researchers has produced the most comprehensive virtual reconstruction ...
Medical research
Mar 03, 2013 |
3.8 / 5 (5) |
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Cancer suppressor gene links metabolism with cellular aging
The tumor suppressor protein p53 is an attractive target for drug developers. But this path has so far proven difficult, as most p53 regulatory proteins operate via protein-protein interactions, which make for poor drug targets, ...
Cancer
Jan 13, 2013 |
3.7 / 5 (3) |
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Study identifies 75 genetic regions that influence red blood cell formation
New research is revealing how red blood cells are made and how the body regulates the amount of haemoglobin that is packaged in red blood cells at any time. Genomic analysis techniques have doubled the number of genetic regions ...
Genetics
Dec 05, 2012 |
4.7 / 5 (3) |
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Study identifies a potential cause of Parkinson's disease
Deciphering what causes the brain cell degeneration of Parkinson's disease has remained a perplexing challenge for scientists. But a team led by scientists from The Scripps Research Institute (TSRI) has pinpointed ...
Parkinson's & Movement disorders
Nov 19, 2012 |
4.3 / 5 (6) |
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Single gene cause of insulin sensitivity may offer insight for treating diabetes
(Medical Xpress)—The first single gene cause of increased sensitivity to the hormone insulin has been discovered by a team of Oxford University researchers.
Diabetes
Sep 12, 2012 |
5 / 5 (3) |
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Using rabies virus, researcher tracks inputs to dopamine neurons
A genetically-modified version of the rabies virus is helping scientists at Harvard to trace neural pathways in the brain, a research effort that could one day lead to treatments for Parkinson's disease and addiction.
Neuroscience
Jun 06, 2012 |
5 / 5 (2) |
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Breast stem-cell research: Receptor teamwork is required and a new pathway may be involved
Breast-cancer researchers at the University of Wisconsin-Madison have found that two related receptors in a robust signaling pathway must work together as a team to maintain normal activity in mammary stem cells.
Cancer
May 30, 2012 |
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BIM gene variation in East Asians found to explain resistance to cancer drugs
A multi-national research team led by scientists at Duke-NUS Graduate Medical School has identified the reason why some patients fail to respond to some of the most successful cancer drugs.
Cancer
Mar 18, 2012 |
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Scientists identify protein that sends 'painful touch' signals
In two landmark papers in the journal Nature this week, scientists at The Scripps Research Institute report that they have identified a class of proteins that detect "painful touch."
Medical research
Feb 19, 2012 |
5 / 5 (2) |
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Gene research sheds light on timing of menopause
(Medical Xpress) -- An international team of researchers has discovered 13 new regions of the genome associated with the timing of menopause.
Genetics
Jan 23, 2012 |
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Tiny worms change direction using two human-like neural circuits
(Medical Xpress) -- A University of Michigan biologist and his colleagues have found that the strategies used by the tiny C. elegans roundworm to control its motions are remarkably similar to those used by ...
Neuroscience
Nov 11, 2011 |
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