Two new phase III clinical trials investigating the efficacy and safety of bitopertin, a glycine uptake inhibitor considered to be a promising new add-on therapy for treating negative symptoms in schizophrenia, failed to ...
Jun 14, 2017
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In the fall of 2015, Rachel Yehuda and her team at the Icahn School of Medicine at Mount Sinai in New York published results of a study looking at the genes of 32 Jewish women and men. All were Holocaust survivors who either ...
Jun 8, 2017
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Life is a series of choices. Every time you make a decision, there is a possibility that things won't go as expected (risk) or that something bad will happen (loss). Aversion to risk and loss have powerful influences on how ...
Jun 6, 2017
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A new study in Biological Psychiatry may pave the way for treating alcohol addiction by reducing motivation to drink, rather than by altering the effects of alcohol itself. Led by Drs. Kasia Radwanska and Leszek Kaczmarek ...
Jun 1, 2017
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Many people have suggested that addiction hijacks the body's natural drives in the service of compulsive drug use. A new study now suggests that hijacking another natural system in the brain may help overcome drug addiction. ...
May 31, 2017
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The human brain functions on a delicate balance of reinforcing positive behaviors and suppressing negative ones, which takes place in the dorsal striatum, a brain region critical for goal-directed behavior and implicated ...
May 25, 2017
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In a special issue of Biological Psychiatry titled "Cortical Excitation-Inhibition Balance and Dysfunction in Psychiatric Disorders", guest editors Dr. Alan Anticevic and Dr. John Murray, both of Yale University, bring together ...
Apr 27, 2017
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A study of people from an isolated village in the Netherlands reveals a link between rare variants in the gene NKPD1 and depressive symptoms. The findings are published in the current issue of Biological Psychiatry. The study, ...
Apr 4, 2017
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Scanning the brains of alcoholics taking medication to beat their addiction has revealed new insights into how the treatments work.
Mar 20, 2017
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The hypocretin/orexin (HCRT) system of the brain is best known for promoting wakefulness and appetite. A new paper in Biological Psychiatry suggests that blocking hypocretin signaling via the HCRT-1 receptor (HCRT-R1) might ...
Mar 16, 2017
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