Immunology

Scientists find missing link between stem cells, immune system

UCLA researchers have discovered a type of cell that is the "missing link" between bone marrow stem cells and all the cells of the human immune system, a finding that will lead to a greater understanding of how a healthy ...

Diseases, Conditions, Syndromes

Common immune response is found to be protective across many diseases

Combined, infection, autoimmunity and cancer account for 4 out of every 10 deaths worldwide, and represent major global health challenges. In a paper in the journal Cell Reports, Institute for Systems Biology (ISB) researchers ...

Immunology

The 'switch' that keeps the immune system from attacking the body

A microscopic battle rages in our bodies, as our cells constantly fend off invaders through our immune system: a complex system of cells and proteins designed to protect us from harmful pathogens. One of its central components ...

Genetics

Researchers uncover genetic factors for severe Lassa fever

While combing through the human genome in 2007, computational geneticist Pardis Sabeti made a discovery that would transform her research career. As a then-postdoctoral fellow at the Broad Institute of MIT and Harvard, Sabeti ...

Diseases, Conditions, Syndromes

Network analysis provides an integrated view of multiple sclerosis

An international research team has developed a computational biology tool, based on multi-level network analysis, to achieve an integrated vision of multiple sclerosis. This tool could be used to study other complex diseases ...

Diseases, Conditions, Syndromes

Researchers trace a form of lupus back to a single mutation

Sometimes a single mutation in our genetic make-up is enough to cause disease. This is also the case with the autoimmune disease lupus. Lupus causes severe inflammation throughout the body and can have a serious impact on ...

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