Parkinson's and multisystem atrophy (MSA), both neurodegenerative diseases, are associated with the accumulation of alpha-synuclein proteins in the brain. Researchers at the German Center for Neurodegenerative Diseases (DZNE) ...
Dec 5, 2019
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Jeremy Smith, Governor's Chair for Molecular Biophysics at the University of Tennessee, Knoxville, and director of the Center for Molecular Biophysics at Oak Ridge National Laboratory, has worked with a research team from ...
Jun 5, 2018
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About half of all melanomas have mutations in the BRAF gene that accelerate tumor cell growth and spread. While most patients benefit from targeted anti-BRAF therapy, resistance to treatment and tumor progression is almost ...
Apr 12, 2018
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More than 20 years after scientists revealed that mutations in the BRCA1 gene predispose women to breast cancer, Yale scientists have pinpointed the molecular mechanism that allows those mutations to wreak their havoc.
Oct 4, 2017
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Columbia University Medical Center (CUMC) researchers have captured the first three-dimensional snapshots of the AMPA-subtype glutamate receptor in action. The receptor, which regulates most electrical signaling in the brain, ...
Jul 24, 2017
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Breaks in DNA can cause chromosome rearrangements, abnormalities linked to cancer. Now Yale scientists have identified how the molecule DNA2 helps begin the complex process of repairing these breaks.
Mar 24, 2017
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The severe learning disabilities of a teenager in the Netherlands were caused by a genetic mutation that affects the function of ribosomes, the cellular protein-making factories crucial to all life. The new finding by an ...
Mar 10, 2017
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"The antidepressant bupropion is a negative allosteric modulator of serotonin type 3A receptors," was published in the September issue of the journal Neuropharmacology.
Oct 28, 2016
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The spreading of cancer cells from one part of the body to another, a process known as metastasis, is the leading cause of death among cancer patients. A study published April 26 in Biophysical Journal now reveals why some ...
Apr 26, 2016
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Professor Armin Giese from the Center for Neuropathology and Prion Research at the LMU Munich and researchers at the Max Planck Institute for Biophysical Chemistry in Göttingen and at the German Center for Neurodegenerative ...
Oct 13, 2015
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