News tagged with biosynthesis

Biosynthesis

Biosynthesis (also called biogenesis) is an enzyme-catalyzed process in cells of living organisms by which substrates are converted to more complex products. The biosynthesis process often consists of several enzymatic steps in which the product of one step is used as substrate in the following step. Examples for such multi-step biosynthetic pathways are those for the production of amino acids, fatty acids, and natural products. Biosynthesis plays a major role in all cells, and many dedicated metabolic routes combined constitute general metabolism.

The prerequisites for biosynthesis are precursor compounds, chemical energy (such as in the form ATP), and catalytic enzymes, which may require reduction equivalents (e.g., in the form of NADH, NADPH).

Commonly known complex products of biosynthesis include proteins, vitamins, and antibiotics. Most organic compounds in living organisms are built in biosynthetic pathways.

This text uses material from Wikipedia and is available under the GNU Free Documentation License.


Gene identified, responsible for a spectrum of disorders affecting the bones and connective tissue

Researchers from the RIKEN Center for Integrative Medical Sciences have identified a gene that when mutated is responsible for a spectrum of disorders affecting the bones and connective tissue. This finding ...

Genetics created May 09, 2013 | popularity not rated yet | comments 0

Modified bone drug kills malaria parasite in mice

A chemically altered osteoporosis drug may be useful in fighting malaria, researchers report in a new study. Unlike similar compounds tested against other parasitic protozoa, the drug readily crosses into ...

Medical research created Feb 27, 2012 | popularity 5 / 5 (4) | comments 1 | with audio podcast

Researchers discover genetic basis for eczema, new avenue to therapies

(Medical Xpress)—Researchers at Oregon State University today announced the discovery of an underlying genetic cause of atopic dermatitis, a type of eczema most common in infancy that also affects millions ...

Inflammatory disorders created Dec 21, 2012 | popularity 5 / 5 (10) | comments 1 | with audio podcast

Study shows key enzyme missing from aggressive form of breast cancer

A groundbreaking new study led by the University of Kentucky Markey Cancer Center's Dr. Peter Zhou found that triple-negative breast cancer cells are missing a key enzyme that other cancer cells contain—providing insight ...

Cancer created Feb 28, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Abuse during childhood linked to uterine fibroids in African-American women

According to a new study from the Slone Epidemiology Center (SEC) at Boston University, African-American women who reported sexual or physical abuse before age 11 had a greater risk of uterine fibroids in adulthood compared ...

Obstetrics & gynaecology created Jan 24, 2013 | popularity not rated yet | comments 0

Common cholesterol drug safe, may improve learning disabilities in patients with neurofibromatosis

Researchers at Children's National Medical Center have found that a cholesterol-lowering statin drug appears to be safe in children with neurofibromatosis type 1 (NF1) and may improve learning disabilities, including verbal ...

Neuroscience created Sep 27, 2011 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Current chemical testing missing low-dosage effects of endocrine-disrupting chemicals

Endocrine-disrupting chemicals (EDCs) -- such as BPA -- can show tangible effects on health endpoints at high dosage levels, yet those effects do not predict how EDCs will affect the endocrine system at low doses, according ...

Immunology created Mar 29, 2012 | popularity not rated yet | comments 0

Key metabolic pathway implicated in intractable form of breast cancer

Using a new in vivo screening system, Whitehead Institute researchers have identified a protein in the serine biosynthesis pathway that is essential in estrogen receptor (ER)-negative breast cancer—a notoriously difficult ...

Cancer created Jul 18, 2011 | popularity not rated yet | comments 0 | with audio podcast