Metabolic disorders play a central role in many common conditions, including Alzheimer's, depression, diabetes and cancer, which call for reliable as well as non-invasive diagnostic procedures. Until now, radioactive substances ...
Apr 28, 2023
0
182
Two proteins ensure that cells can take up iron when needed. If both control proteins are switched off in mice, the animals develop severe anemia, as expected. At the same time, surprisingly, a cell type of the innate immune ...
Oct 7, 2022
0
67
Injections of an engineered antibody known as AMY109, given every month, were found to reduce lesion volume and lessen scar tissue and organ adhesions in monkeys with endometriosis.
A new method to cure HIV—by transplanting HIV-resistant stem cells from umbilical cord blood—has yielded long-term successful results, say scientists. The approach was successfully used to treat the "New York patient," ...
Mar 16, 2023
0
138
For the longest time, clinicians have treated cardiovascular disease by focusing on diabetes and blood pressure control, reducing cholesterol using medications like aspirin and statins.
Dec 15, 2022
0
34
A new study published in Nature Genetics led by the Mead Group in the Radcliffe Department of Medicine has demonstrated a previously unknown effect of chronic inflammation on TP53-mutant hematopoietic stem cells.
Sep 8, 2023
0
253
Cambridge scientists have grown small blood vessel-like models in the lab and used them to show how damage to the scaffolding that supports these vessels can cause them to leak, leading to conditions such as vascular dementia ...
Nov 16, 2023
0
76
A study at Karolinska Institutet shows that the coronavirus variant BA.2.75.2, an omicron sublineage, largely evades neutralizing antibodies in the blood and is resistant to several monoclonal antibody antiviral treatments. ...
Oct 14, 2022
0
135
Microglia are primary immune cells that safeguard the mammalian brain, partly by devouring or 'phagocytosing' pathogens and toxic debris. Recent genetic studies have consistently highlighted the role of microglia in the development ...
Introducing bacteria to a tumor's microenvironment creates a state of acute inflammation that triggers the immune system's primary responder cells to attack rather than protect a tumor, according to a new study from the Garvan ...
Mar 13, 2023
0
101
