Diseases, Conditions, Syndromes

Gene-edited malaria vaccine warrants further study

Findings from a preliminary human study of an experimental, genetically attenuated malaria parasite immunization show this vaccine warrants further exploration.

Immunology

How the immune system builds long-term memory

Experts in Japan have identified a fundamental part of the immune system's long-term memory, providing a useful new detail in the pursuit to design better vaccines for diseases, ranging from COVID-19 to malaria. The research, ...

Diseases, Conditions, Syndromes

Blocking how the malaria parasite suppresses the immune response

The parasites that cause severe malaria are well-known for the sinister ways they infect humans, but new research may lead to drugs that could block one of their most reliable weapons: interference with the immune response.

Diseases, Conditions, Syndromes

Microscopic CCTV reveals secrets of malaria invasion

State-of-the-art video microscopy has enabled researchers at WEHI, Australia, to see the molecular details of how malaria parasites invade red blood cells—a key step in the disease.

Diseases, Conditions, Syndromes

Hidden malaria life cycle discovered in the spleen

Groundbreaking studies published today in the New England Journal of Medicine and PLOS Medicine have found large numbers of malaria parasites hiding in the human spleen where they actively multiply in a previously unrecognized ...

Medications

Scientists design new drug compound to stop malaria in its tracks

Researchers at the Francis Crick Institute and the Latvian Institute of Organic Synthesis have designed a drug-like compound which effectively blocks a critical step in the malaria parasite life cycle and are working to develop ...

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