Diseases, Conditions, Syndromes

What is the ACE2 receptor, and how is it connected to coronavirus?

In the search for treatments for COVID-19, many researchers are focusing their attention on a specific protein that allows the virus to infect human cells. Called the angiotensin-converting enzyme 2, or ACE2 "receptor," the ...

Medical research

Tumors' mechanical properties affect protein production

Tissues stiffen with age, poor diet, disease and for natural reasons, and when they do, a new study shows, proteins produced by such cells can be altered, which in turn affects downstream processes.

Medical research

Putting the brakes on accelerated aging

Telomeres are to chromosomes what aglets are to shoelaces—protective caps that stop the tightly wound strings from unraveling. Every time a cell divides, its telomeres are trimmed, eventually becoming so short that the ...

Medications

How a widely used diabetes medication actually works

Physicians have used the drug metformin to treat type 2 diabetes for more than half a century, but despite its prevalence, researchers have lacked a clear understanding of how it works. Now, Yale researchers have elucidated ...

Immunology

Pathway to resolve allergic asthma is discovered

A group of Brazilian researchers succeeded in preventing allergic asthma from progressing in experimental models by increasing the amount of a certain protein. This increase, in turn, blocked the CD4+ T lymphocytes responsible ...

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