Health

Ketogenic diets alter gut microbiome in humans, mice

Low-carb, high-fat ketogenic diets, which have attracted public interest in recent years for their proposed benefits in lowering inflammation and promoting weight loss and heart health, have a dramatic impact on the microbes ...

Gerontology & Geriatrics

How interval training affects 'belly fat' in obese 70-year-olds

By today's estimates, one-third of adults aged 65 or older are obese. This growing obesity trend, along with the decrease in our level of physical activity as we age, seriously raises our risk of diseases and death.

Medical research

Mimicking calorie restriction to fight obesity, type 2 diabetes

A Yale University-led research team has discovered how reduced expression of a particular gene protects against obesity and type 2 diabetes, possibly prolonging lifespan by mimicking the effects of calorie restriction. The ...

Cardiology

Researchers develop more accurate measure of body fat

Cedars-Sinai investigators have developed a simpler and more accurate method of estimating body fat than the widely used body mass index, or BMI, with the goal of better understanding obesity.

Overweight & Obesity

I go to the gym every day. Why can't I lose weight?

Liz is a typical 50-something woman, fit, 70 kg, 30% body fat. She goes to the gym every day, and runs for 35 minutes on the treadmill at 10km/h. But, as she tells me rather often, she can't lose weight. So what's going on ...

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Adipose tissue

In histology, adipose tissue or body fat or just fat is loose connective tissue composed of adipocytes. Adipose tissue is derived from lipoblasts. Its main role is to store energy in the form of fat, although it also cushions and insulates the body. Obesity or being overweight in humans and most animals does not depend on body weight but on the amount of body fat—specifically, adipose tissue. Two types of adipose tissue exist: white adipose tissue (WAT) and brown adipose tissue (BAT). Adipose tissue also serves as an important endocrine organ by producing hormones such as leptin, resistin and the cytokine TNFα. The formation of adipose tissue appears to be controlled by the adipose gene. Adipose tissue was first identified by the Swiss naturalist Conrad Gessner in 1551.\

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