Scientists discover mechanism of resistance to vital leukaemia treatment, opening door to new therapies
(Medical Xpress)—Research published in the journal Cancer Cell has revealed the mechanism by which leukaemia cells develop resistance to the ATRA (All-Trans-Retinoic Acid) treatment, used to treat an agg ...
Cancer
Mar 19, 2013 |
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Two new genes linked to amyotrophic lateral sclerosis and related disorders
(Medical Xpress)—A study led by St. Jude Children's Research Hospital has discovered mutations in two genes that lead to the death of nerve cells in amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, ...
Genetics
Mar 18, 2013 |
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White blood cells found to play key role in controlling red blood cell levels
Researchers at Albert Einstein College of Medicine of Yeshiva University and the Icahn School of Medicine at Mount Sinai have found that macrophages – white blood cells that play a key role in the immune response – also ...
Medical research
Mar 17, 2013 |
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Cellular bells: Key step in manufacture of red blood cells decoded
A healthy adult must generate as many as one hundred billion new red blood cells each day, to maintain the numbers circulating in his blood. A team of EPFL researchers has identified a key step in the process by which red ...
Medical research
Mar 14, 2013 |
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Sizing up bone growth: A surprising cellular mechanism drives skeletal proportions
(Medical Xpress)—Stroll through the Harvard Museum of Natural History and gaze up at the whale skeleton looming overhead. Look down at the furry foxes curled up inside their glass display cases. Don't forget ...
Medical research
Mar 14, 2013 |
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Researchers find NSAIDs help push stem cells into bloodstream prior to transplantation
(Medical Xpress)—A team of researchers at Indiana University's School of Medicine has found that giving meloxicam, a non-steroidal anti-inflammatory drug (NSAID), to people and baboons boosts the number of haematopoietic ...
Medical research
Mar 14, 2013 |
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New methods help to improve attachment of an implant to bone
Replacement of prostheses is unpleasant to the patient and expensive to society. Replacement of failed hip prostheses gives rise to an expenditure of about 10 million euros yearly in Finland. A usual reason ...
Medical research
Mar 13, 2013 |
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Researchers use a type of stem cells from human adipose tissue to chase migrating cancer cells
In laboratory studies, Johns Hopkins researchers say they have found that stem cells from a patient's own fat may have the potential to deliver new treatments directly into the brain after the surgical removal of a glioblastoma, ...
Cancer
Mar 12, 2013 |
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Study finds fat and bone mass are genetically linked
When it comes to body shape, diet and exercise can only take us so far. Our body shape and geometry are largely determined by genetic factors. Genetics also have an impact on our body composition – including soft fat tissue ...
Medical research
Mar 11, 2013 |
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When bone-eating cells gain the upper hand
Advanced osteoporosis is often the most severe sequela, or resulting condition, of plasma cell cancer (multiple myeloma). Abnormally functioning stem cells are a key causal factor.
Medical research
Mar 11, 2013 |
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Biological tooth replacement—a step closer
Scientists have developed a new method of replacing missing teeth with a bioengineered material generated from a person's own gum cells. Current implant-based methods of whole tooth replacement fail to reproduce a natural ...
Dentistry
Mar 09, 2013 |
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Signaling molecule may help stem cells focus on making bone despite age, disease
A signaling molecule that helps stem cells survive in the naturally low-oxygen environment inside the bone marrow may hold clues to helping the cells survive when the going gets worse with age and disease, ...
Medical research
Mar 08, 2013 |
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Novel treatment for bone marrow cancer
Multiple myeloma is a form of cancer in which the plasma cells in the bone marrow grow out of control, causing damage to bones as well as predisposing patients to anaemia, infection and kidney failure. A ...
Cancer
Mar 07, 2013 |
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A better bone marrow transplant: Preventing graft-versus-host disease
Bone marrow transplant is a key treatment for patients with leukemia, lymphoma, multiple myeloma and other blood disorders.
Medical research
Mar 01, 2013 |
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Eat too much? Maybe it's in the blood
Bone marrow cells that produce brain-derived eurotrophic factor (BDNF), known to affect regulation of food intake, travel to part of the hypothalamus in the brain where they "fine-tune" appetite, said researchers from Baylor ...
Medical research
Feb 26, 2013 |
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