Denosumab reduces burden of giant-cell tumor of the bone
Treatment with denosumab, a drug targeted against a protein that helps promote bone destruction, decreased the number of tumor giant cells in patients with giant-cell tumor of the bone, and increased new bone formation, according ...
Cancer
Sep 21, 2012 |
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'Half-match' bone marrow transplants wipe out sickle cell disease in selected patients
In a preliminary clinical trial, investigators at Johns Hopkins have shown that even partially-matched bone marrow transplants can eliminate sickle cell disease in some patients, ridding them of painful and debilitating symptoms, ...
Medical research
Sep 20, 2012 |
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Researcher develops new coating to help bone implants last
(Medical Xpress)—Two Colorado State University professors have developed a nanostructured surface coating for bone that is expected to help improve the lifetime of bone implants.
Medical research
Sep 20, 2012 |
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Lack of sleep affects bone health and bone marrow activity
Scientists at the Medical College of Wisconsin, in a team led by Carol Everson, Ph.D., professor of neurology, cell biology, neurobiology and anatomy, have discovered abnormalities in bone and bone marrow in rats undergoing ...
Medical research
Sep 18, 2012 |
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Researchers find novel predictor for MDS progression risk
Researchers at Moffitt Cancer Center and colleagues have discovered that changes in the physical characteristics of the effector memory regulatory T cell can predict the progression risk of myelodysplastic syndromes (MDS) ...
Immunology
Sep 13, 2012 |
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Researchers restore children's immune systems with refinements in gene therapy
Researchers have demonstrated that a refined gene therapy approach safely restores the immune systems of some children with severe combined immunodeficiency (SCID). The rare condition blocks the normal development of a newborn's ...
Immunology
Sep 11, 2012 |
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Race, ethnicity affect likelihood of finding suitable unrelated stem cell donor for cancer patients
(Medical Xpress)—Researchers at Moffitt Cancer Center and colleagues have published a study describing the greater difficulty in finding matched, unrelated donors for non-Caucasian patients who are candidates for hematopoietic ...
Cancer
Sep 11, 2012 |
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Improved diagnostic test benefits children with acute myeloid leukemia
Early treatment response is a powerful predictor of long-term outcome for young patients with acute myeloid leukemia (AML). The information can help physicians decide whether a more intensive approach is needed. Research ...
Cancer
Sep 10, 2012 |
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Can gene therapy cure fatal diseases in children?
In order for the body to function, a balance is necessary between the cells that build up the bones in our skeletons and the cells that break them down. In the disease malignant infantile osteopetrosis, MIOP, the cells that ...
Genetics
Sep 05, 2012 |
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Possible new therapy for the treatment of myeloma
(Medical Xpress)—Research from Karolinska Institutet shows that sorafenib, a drug used for advanced cancer of the kidneys and liver, could also be effective against multiple myeloma. The disease is one of the more common ...
Cancer
Sep 05, 2012 |
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FDA approves Pfizer drug for rare blood cancer
Pfizer Inc. says the Food and Drug Administration on Tuesday approved its new drug to treat a rare form of blood and bone marrow cancer.
Medications
Sep 04, 2012 |
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New genetic clues to why most bone marrow transplant patients develop graft-versus-host disease
A team of scientists led by a bone marrow transplant researcher at Fred Hutchinson Cancer Research Center has shed new light on why most bone marrow transplant patients who receive tissue-matched cells from unrelated donors ...
Medical research
Sep 04, 2012 |
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EU approves Novartis-Incyte blood cancer drug
Novartis AG and Incyte Corp. said Tuesday that European Union regulators approved their blood cancer drug Jakavi.
Medications
Sep 04, 2012 |
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Tapping the body to fight disease
Biju Parekkadan saw his future in the plight of a newborn thousands of miles away.
Medical research
Sep 03, 2012 |
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Stem cell-powered implant set to revolutionize orthopedic surgery (w/ Video)
Scientists at the University of Glasgow are working to harness the regenerative power of stem cells to improve orthopaedic implant surgery.
Surgery
Sep 03, 2012 |
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