Mutations of the alkaline phosphatase (ALPL) gene in the liver, bone and kidney can cause hypophosphatasia (HPP) and early-onset bone dysplasia, asserting its key role in human bone development. Despite its importance, its ...
Imagine being able to count the different types of blood cells being formed inside the tiny bones of a mouse and pinpointing the strings and clusters of cells within the bone marrow that are responsible for producing specific ...
Mar 20, 2024
0
14
Cancer patients who receive radiation during their treatment—and about half do—may face a lesser-known challenge: bone loss. The vital treatment for cancers of the head and neck, breast, cervix, prostate, and even eyes ...
Dec 6, 2023
0
69
Artificial intelligence has exploded in popularity and is being harnessed by some scientists to predict which molecules could treat illnesses, or to quickly screen existing medicines for new applications.
Oct 18, 2023
0
63
A UC Davis Health study that looked at acute bone loss in mice who had COVID-19 showed that SARS‐CoV‐2 infection can cause significant changes in bone structure. The study, published in the Journal of Orthopaedic Research, ...
Jul 24, 2023
0
137
Taking good care of your teeth may be linked to better brain health, according to a study published in the July 5, 2023, online issue of Neurology. The study found that gum disease and tooth loss were linked to brain shrinkage ...
Jul 5, 2023
0
206
The bones of the face and skull can be affected due to a wide range of conditions, including cleft palate defects, traumatic injuries, cancer, and bone loss from dentures. Although bone replacements are routinely used to ...
Feb 22, 2023
0
112
Elevated levels of air pollutants are associated with bone damage among postmenopausal women, according to new research led by scientists at Columbia University Mailman School of Public Health. The effects were most evident ...
Feb 21, 2023
0
63
A topical gel that blocks the receptor for a metabolic byproduct called succinate treats gum disease by suppressing inflammation and changing the makeup of bacteria in the mouth, according to a new study led by researchers ...
Sep 20, 2022
0
124
A team of researchers at Fourth Military Medical University, in China, working with a colleague from Shaanxi University of Chinese Medicine, has found that the application of a pulsed electromagnetic field (PEMF) following ...
Osteoporosis is a disease of bone that leads to an increased risk of fracture. In osteoporosis the bone mineral density (BMD) is reduced, bone microarchitecture is disrupted, and the amount and variety of non-collagenous proteins in bone is altered. Osteoporosis is defined by the World Health Organization (WHO) in women as a bone mineral density 2.5 standard deviations below peak bone mass (20-year-old healthy female average) as measured by DXA; the term "established osteoporosis" includes the presence of a fragility fracture. Osteoporosis is most common in women after menopause, when it is called postmenopausal osteoporosis, but may also develop in men, and may occur in anyone in the presence of particular hormonal disorders and other chronic diseases or as a result of medications, specifically glucocorticoids, when the disease is called steroid- or glucocorticoid-induced osteoporosis (SIOP or GIOP). Given its influence is the risk of fragility fracture, osteoporosis may significantly affect life expectancy and quality of life.
Osteoporosis can be prevented with lifestyle changes and sometimes medication; in people with osteoporosis, treatment may involve both. Lifestyle change includes preventing falls and exercise; medication includes calcium, vitamin D, bisphosphonates and several others. Fall-prevention advice includes exercise to tone deambulatory muscles, proprioception-improvement exercises; equilibrium therapies may be included. Exercise with its anabolic effect, may at the same time stop or reverse osteoporosis.
This text uses material from Wikipedia, licensed under CC BY-SA
