Researchers from the University of Tokyo reveal how the presynaptic Ube3a E3 ligase, a causal factor in Angelman syndrome, eliminates neural chatter. The study helps find a better drug target for the Angelman syndrome treatment.
Sep 14, 2023
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46
In the gym, you are not just pumping iron, you are oxygenating muscle cells which keeps those muscles healthy, strong and growing—a process called hypertrophy, or an increase in muscle mass due to an increase in muscle ...
Apr 27, 2022
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118
Given enough time and energy, the body will heal, but when doctors or engineers intervene, the processes do not always proceed as planned because chemicals that control and facilitate the healing process are missing. Now, ...
Apr 12, 2022
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75
By replacing or replenishing injured tissue with biomimetic structures, scientists can help initiate stem cell-driven repair cascades throughout the body. Insights from an A*STAR-led study of the interactions between bone ...
Mar 18, 2019
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1
Mesenchymal stem cells (MSCs) are a promising cell source, easy to harvest and differentiate into a variety of mesodermal tissues including fat, bone and cartilage in regenerative medicine. However, for in vivo implantation, ...
Researchers have produced stable joint cartilage from adult stem cells originating from bone marrow. This was made possible by inducing specific molecular processes occurring during embryonic cartilage formation, as researchers ...
Apr 17, 2018
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1215
When prostate cancer metastasizes to bone, it can become especially dangerous - not only with its action in the bone but, interestingly, with increased aggressiveness of the overall cancer itself. Now, research presented ...
Apr 16, 2018
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5
When a patient breaks a bone, there's a possibility the fracture won't heal properly or quickly—even with the aid of pins, plates or a cast.
Feb 1, 2018
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77
A new study has shown that heparan sulfate, a desirable natural material for use in bioengineered tissues and orthotic implants, can withstand the stress of gamma irradiation for sterilization and retain its structure, binding ...
Jan 25, 2018
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2
This year's Broad Clinical Research Fellows will apply stem cell-based approaches to two prevalent problems: non-healing bone injuries, which affect 5 million Americans each year, and neuroblastoma, the most common solid ...
Jan 25, 2018
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