While rare, botulism can cause paralysis and is potentially fatal. It is caused by nerve-damaging toxins produced by Clostridium botulinum—the most potent toxins known. These toxins are often found in contaminated food ...
Jan 8, 2021
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Botulinum toxin (BoNT) is used for a range of applications from treating chronic pain to reducing the appearance of wrinkles, but when injected it can diffuse into the surrounding tissue and give rise to adverse effects. ...
Mar 17, 2020
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Researchers have identified a compound that strongly inhibits botulinum neurotoxin, the most toxic compound known. That inhibiting compound, nitrophenyl psoralen (NPP), could be used as a treatment to reduce paralysis induced ...
Nov 2, 2018
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A modified form of botulinum toxin gives long-lasting pain relief in mice without adverse effects and, in time, could replace opioid drugs as a safe and effective way of treating chronic pain, according to research by UCL, ...
Jul 18, 2018
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The botulinum toxins are among the deadliest substances on Earth, and two specific toxins—including the popular drug Botox—have multiple uses for treating many neuromuscular conditions, including frown lines, disabling ...
Aug 4, 2016
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UC Irvine School of Medicine researchers have discovered the mechanism by which bacterial toxins that cause food-borne botulism are absorbed through the intestinal lining and into the bloodstream. Their study, which appears ...
Jun 19, 2014
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National Institutes of Health researchers used the popular anti-wrinkle agent Botox to discover a new and important role for a group of molecules that nerve cells use to quickly send messages. This novel role for the molecules, ...
May 2, 2013
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(Medical Xpress)—Botulinum toxins are feared as a food poison and bioterror threat, and for good reason. It takes only minute amounts of these bacterial toxins to block signals from nerve cells that control muscles. People ...
Mar 27, 2013
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Researchers have unveiled a novel strategy for neutralizing unwanted molecules and clearing them from the body.
Jun 18, 2012
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Researchers at Sanford-Burnham Medical Research Institute (Sanford-Burnham) and the Medical School of Hannover in Germany recently discovered how the botulinum neurotoxin, a potential bioterrorism agent, survives the hostile ...
Feb 23, 2012
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