A new strategy for repairing DNA damage in neurons
"Use it or lose it" goes the adage, applied liberally to everything from our muscles to our minds, especially as we age.
Feb 15, 2023
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1211
"Use it or lose it" goes the adage, applied liberally to everything from our muscles to our minds, especially as we age.
Feb 15, 2023
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1211
A common sign of Alzheimer's disease is the excessive buildup of two types of protein in the brain: tangles of tau proteins that accumulate inside cells, and amyloid-β proteins that form plaques outside the cells. Researchers ...
Feb 2, 2023
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471
An experimental antidepressant compound with a potentially unique mechanism of action may also be effective against alcohol use disorder, according to a preclinical study from Scripps Research.
Jan 30, 2023
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61
It's a good news, bad news story. Patients whose brain tumors have a mutated enzyme called IDH1 typically live longer than those without the mutation. But even as these tumors are initially less aggressive, they always come ...
Jan 24, 2023
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19
The outer layer of the human brain (the cerebral cortex), characterized by its distinctive gyri and sulci (those distinctive ridges and furrows), controls cognitive and executive function, from conscious thought to speech ...
Jan 18, 2023
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151
University of Virginia neuroscientists have revealed how a toxic form of tau protein, notorious for forming tangles in the brains of people with Alzheimer's disease and several other neurodegenerative disorders, spreads through ...
Jan 12, 2023
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Alzheimer's disease begins decades before the onset of any symptoms, such as memory loss. Consequently, early diagnosis increases the chances of slowing the disease down with drugs. A new study on an inherited form of the ...
Jan 10, 2023
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A new USC Leonard Davis School of Gerontology study challenges existing ideas of how buildup of a protein called amyloid beta (Aβ) in the brain is related to Alzheimer's disease.
Jan 6, 2023
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76
A new drug designed to ward off Alzheimer's is being tested at more than 100 sites around the world, including the University of Pennsylvania.
Dec 29, 2022
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25
In November, researchers reported the drug lecanemab slowed the progression of Alzheimer's disease. The effect was modest, but it has generated tremendous excitement because it was the first time a drug had been shown to ...
Dec 27, 2022
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107