Oncology & Cancer

Localizing BRCA gene mutations to better treat ovarian cancer

Mutations of BRCA1 and BRCA2 genes, which are inherited by 1 in 400 and 1 in 800 people respectively, significantly increase the risk of certain cancers such as ovarian, breast, pancreatic and prostate cancer.

Oncology & Cancer

Faulty DNA repair may lead to BRCA-linked cancers

Error-prone DNA replication and repair may lead to mutations and cancer in individuals who inherit a mutant copy of the BRCA1 gene, according to a new study by Weill Cornell Medicine investigators. The discovery has potential ...

Oncology & Cancer

Variants in BRCA1/2 and MMR genes in children with cancer

Pathogenic variants in BRCA1/2 genes are associated with an increased risk of breast and ovarian cancer in adults, and variants in mismatch repair (MMR) genes increase the risk of gastrointestinal and other cancers. Until ...

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