It is estimated that between 5% and 10% of breast and ovarian cancers are familial in origin, which is to say that these tumours are attributable to inherited mutations from the parents in genes such as BRCA1 or BRCA2. In ...
Jun 18, 2013
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(Medical Xpress)—When people think about genes and their relationship to cancer, most probably think about a person's hereditary cancer risk, especially after Angelina Jolie's recent news about her inherited breast and ...
Jun 18, 2013
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In the largest clinical trial to date to examine the efficacy of PARP inhibitor therapy in BRCA 1/2 carriers with diseases other than breast and ovarian cancer, the oral drug olaparib was found to be effective against advanced ...
May 15, 2013
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Actress Angelina Jolie has today written an op-ed in the New York Times explaining that she has opted to have a double mastectomy because she carries the hereditary BRCA1 gene, which she says increases her risk of breast ...
May 15, 2013
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Women whose genes put them at a high risk of contracting breast cancer can dramatically reduce the danger by having a double mastectomy—but not eliminate it altogether, experts say.
May 14, 2013
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Patients with prostate cancer and hereditary mutations in the BRCA2 gene have a worse prognosis and lower survival rates than do the rest of the patients with the disease. This is the main conclusion to come out of a study ...
Apr 9, 2013
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Patients with breast cancer who had a BRCA1 mutation had significantly worse overall and recurrence-free survival rates compared with patients without BRCA mutations, but no evidence for a difference in survival was found ...
Apr 9, 2013
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Researchers at Mayo Clinic Cancer Center have identified new DNA sequences associated with breast cancer—the most common cancer among women, with an average risk of developing the disease of 10 percent—and ovarian cancer, ...
Mar 27, 2013
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An international research collaboration has found five new regions of the human genome that are linked to increased risks for developing ovarian cancer. Duke Medicine researchers played a leading role analyzing genetic information ...
Mar 27, 2013
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A 23andMe study of consumers' reactions to genetic testing found that even when the tests revealed high-risk mutations in individuals, those individuals had few negative reactions to the news. Instead of inducing serious ...
Feb 12, 2013
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