Ability to metabolize tamoxifen affects breast cancer outcomes, study confirms
For nearly a decade, breast cancer researchers studying the hormone therapy tamoxifen have been divided as to whether genetic differences in a liver enzyme affect the drug's effectiveness and the likelihood breast cancer ...
Cancer
Dec 27, 2012 |
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Healthy lifestyle during menopause may decrease breast cancer risk later on
Obese, postmenopausal women are at greater risk for developing breast cancer and their cancers tend to be more aggressive than those in lean counterparts. A University of Colorado Cancer Center study published in the December ...
Cancer
Dec 19, 2012 |
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New small molecule inhibitor could be a safe and first-line treatment for metastatic breast cancer
Previous research has shown that a family of genes, proteins and enzymes called the uPA system (for urokinase plasminogen activator) plays an active role in different facets of cancer's biology, including tumor cell invasion, ...
Cancer
Dec 08, 2012 |
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Avastin won't extend breast cancer survival: study
(HealthDay)—The drug Avastin (bevacizumab), when added to chemotherapy, does not improve disease-free survival in patients with triple-negative breast cancer any better than chemo alone, new research finds.
Medications
Dec 07, 2012 |
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Protein tied to cancer drug resistance in mice
Blocking a specific protein renders tumors more vulnerable to treatment in mice, suggesting new therapies could eventually achieve the same in humans, according to new research from Fox Chase Cancer Center to be presented ...
Cancer
Dec 07, 2012 |
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TGen-US Oncology data guides treatment of metastatic triple-negative breast cancer patients
Genomic sequencing has revealed therapeutic drug targets for difficult-to-treat, metastatic triple-negative breast cancer (TNBC), according to an unprecedented study by the Translational Genomic Research Institute (TGen) ...
Cancer
Dec 06, 2012 |
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Tamoxifen trial should prompt breast cancer patients to reconsider treatment options
A groundbreaking clinical trial involving the breast cancer drug tamoxifen should prompt certain breast cancer patients to reconsider their treatment options, according to Loyola University Medical Center breast cancer specialist ...
Cancer
Dec 06, 2012 |
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10 years of tamoxifen better than 5, study reports
(HealthDay) —Taking the breast cancer drug tamoxifen for a decade, instead of the standard five years, further reduces the long-term chances of recurrence and risk of dying from the disease, new British ...
Cancer
Dec 05, 2012 |
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New drug regimens may slow advanced breast cancer
(HealthDay)—An experimental cancer drug may delay the progression of some advanced breast cancers, while a double dose of an existing cancer drug could help women live longer, according to separate studies ...
Cancer
Dec 05, 2012 |
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Breast cancer drug could hold the key to fighting other tumours
New research out of the United Kingdom is showing that a common drug used in the fight against breast cancer could also be employed in the fight against other tumours. The drug in question is geldanamycin, ...
Cancer
Dec 05, 2012 |
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Improving chemotherapy effectiveness by acting on the immune system
An Inserm team in Dijon directed by François Ghiringhelli is to publish an article this week in the Nature Medicine review. The article suggests that two chemotherapy drugs frequently used to treat digestive and breast cancers ...
Immunology
Dec 04, 2012 |
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Grief is not a disease, but cancer is: What about erectile dysfunction or gambling addiction?
"Understanding peoples' attitudes about whether states of being should be considered diseases can inform social discourse regarding a number of contentious social and health public policy issues," says Kari ...
Health
Dec 03, 2012 |
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Researchers develop novel treatment for prostate cancer
(Medical Xpress)—The work of a team of Wake Forest researchers developing a novel drug for prostate cancer treatment is featured on the cover of the Nov. 26 issue of the Journal of Medicinal Chemistry.
Cancer
Nov 29, 2012 |
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Researchers link new molecular culprit to breast cancer progression
(Phys.org)—Johns Hopkins researchers have uncovered a protein "partner" commonly used by breast cancer cells to unlock genes needed for spreading the disease around the body. A report on the discovery, published November ...
Cancer
Nov 25, 2012 |
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MicroRNA makes triple-negative breast cancer homesick
Epithelial cells are homebodies – they like to attach to things and becoming detached initiates a form of cell suicide known as anoikis (literally "homeless" in Latin). But in order for cancer cells to metastasize they ...
Cancer
Nov 21, 2012 |
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