Scientists from The University of Manchester have shown that testing for two gene families linked to a lifetime epithelial ovarian cancer risk of between 5% and 20% has a much higher than expected detection rate.
Oct 4, 2022
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Every cell has two mechanisms for repairing DNA single- or double-strand breaks, which can be induced by such factors as environmental toxins, chemotherapy, or ionizing radiation. The first one consists of the DNA repair ...
Sep 21, 2022
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In a recent study published in JAMA Oncology, investigators from the University of Bergen, in collaboration with the Women's Health Initiative (WHI) study in the U.S., reported epigenetic gene silencing in normal tissue to ...
Sep 20, 2022
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Just as bacteria, viruses and fungi develop strategies to outsmart antimicrobial medications, cancer cells can become resistant to chemotherapy. And among tumors, those associated with triple negative breast cancer and ovarian ...
Cleveland Clinic researchers have uncovered genomic characteristics of breast cancers associated with PTEN hamartoma tumor syndrome (PHTS) that differentiate them from sporadic breast cancers. The findings, published in the ...
Aug 4, 2022
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Telling a child about their mother's risk of hereditary breast and ovarian cancer does not adversely influence the offspring's lifestyle or quality of life in the long term, according to a new study led by researchers at ...
Jul 21, 2022
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Alzheimer's disease (AD) is a progressive neurodegenerative disorder and the most common cause of dementia, affecting more than 5.8 million individuals in the U.S. Scientists have discovered some genetic variants that increase ...
Jun 30, 2022
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Chronically stressful conditions of daily life such as racism, pollution and poverty have a direct impact on the cellular mechanisms that drive lethal, invasive forms of breast cancer, according to a study led by Duke Cancer ...
Jun 13, 2022
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A research paper titled "A novel group of genes that cause endocrine resistance in breast cancer identified by dynamic gene expression analysis" was recently published in Oncotarget.
Jun 8, 2022
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Women of African ancestry more often have a personal history of triple-negative breast cancer (TNBC), but the magnitudes of gene-specific risks for TNBC are similar across different racial/ethnic groups, according to a study ...
Jun 8, 2022
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