In animal studies led by researchers at Duke Cancer Institute, a drug approved to treat leukemia successfully disrupted the ability of HER2-positive breast cancer tumors from colonizing the brain.
Aug 31, 2022
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Scientists at Weill Cornell Medical College have discovered the molecular switch that allows aggressive triple negative breast cancer cells to grow the amoeba-like protrusions they need to crawl away from a primary tumor ...
Jan 14, 2013
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(Medical Xpress)—Nancy Hynes and her group at the Friedrich Miescher Institute for Biomedical Research have discovered an important mediator of breast cancer metastasis. The protein called Memo is not only required for ...
Jun 20, 2014
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(Medical Xpress) -- Scientists are one step closer to repairing the damage caused by brain metastasis, a major challenge in cancer treatment, according to data published in Cancer Research, a journal of the American Association ...
Jan 3, 2012
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The finding involves the cancer gene RhoC, which has previously been shown to promote metastasis of many types of cancer. RhoC levels increase as breast cancer progresses and high levels of RhoC are associated with worse ...
Jul 24, 2012
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A study headed by Salvador Aznar Benitah, ICREA researcher at the Institute for Research in Biomedicine (IRB Barcelona), and published today in Nature identifies metastasis-initiating cells through a specific marker, namely ...
Dec 7, 2016
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A protein naturally produced in the body has been found to suppress breast cancer metastasis in animal models of human tumors. Researchers led by Baylor College of Medicine also found that high levels of this protein, AKAP8, ...
Jan 27, 2020
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Researchers and clinicians don't fully understand why some cancers spread and others do not. What they do know is that when cancer does spread, it dramatically decreases survival rates.
May 20, 2019
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(Medical Xpress) -- Trinity College Dublin researchers have discovered that blocking a particular stress response can significantly reduce the metastasis (or spread) of breast cancer.
Jun 1, 2011
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The nuclear envelope (NE) is composed of the outer nuclear membrane (ONM) and the inner nuclear membrane (INM), which are separated by the perinuclear space and joined at nuclear pore complexes. INM proteins play crucial ...
Dec 8, 2021
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