News tagged with breast carcinoma


DCIS Score quantifies risk of ipsilateral breast event

The ductal carcinoma in situ (DCIS) Score quantifies the risk of ipsilateral breast event (IBE) and invasive IBE risk, complements both traditional clinical and pathologic factors, and helps provide a new clinical tool to ...

Cancer created May 02, 2013 | popularity not rated yet | comments 0

Big data analysis identifies prognostic RNA markers in a common form of breast cancer

A Big Data analysis that integrates three large sets of genomic data available through The Cancer Genome Atlas has identified 37 RNA molecules that might predict survival in patients with the most common form of breast cancer.

Cancer created Apr 29, 2013 | popularity not rated yet | comments 0 | with audio podcast

Tomosynthesis improves detection of infiltrating ductal carcinoma in patients with increased risk

Tomosynthesis (3D mammography) is better able to show infiltrating ductal carcinoma than 2D mammography in women at increased risk of breast cancer, a new study shows.

Cancer created Apr 13, 2013 | popularity not rated yet | comments 0

Quantifying heterogeneity in breast cancer

A variety of mutations may give rise to breast cancer, but scientists generally assume that it starts off with just a few. That's because later-stage breast cancers tend to have more mutations—they are more heterogeneous—than ...

Cancer created Apr 09, 2013 | popularity not rated yet | comments 0

Combined RB and PTEN loss identifies DCIS primed for invasive breast cancer

The combined loss of two tumor suppressor genes, retinoblastoma (RB) and phosphatase and tensin homolog (PTEN) was shown to be strongly associated with progression of DCIS to invasive breast cancer, according to a study published ...

Cancer created Nov 28, 2012 | popularity not rated yet | comments 0

MicroRNA makes triple-negative breast cancer homesick

Epithelial cells are homebodies – they like to attach to things and becoming detached initiates a form of cell suicide known as anoikis (literally "homeless" in Latin). But in order for cancer cells to metastasize they ...

Cancer created Nov 21, 2012 | popularity 5 / 5 (2) | comments 0 | with audio podcast

George Mason University researchers target breast cancer in three trials

A malarial drug is showing promise in stopping breast cancer before it starts, Mason researchers are discovering during a clinical trial.

Cancer created Nov 01, 2012 | popularity not rated yet | comments 0

New study sheds new light on the progression and invasiveness of ductal breast cancer

Ductal carcinoma in situ (DCIS) is considered a precursor lesion for invasive breast cancer if untreated, and is found in approximately 45% of patients with invasive ductal carcinoma (IDC). Patients with DCIS only (not accompanied ...

Cancer created Oct 16, 2012 | popularity not rated yet | comments 0

Prostate cancer: Curcumin curbs metastases

Powdered turmeric has been used for centuries to treat osteoarthritis and other illnesses. Its active ingredient, curcumin, inhibits inflammatory reactions. A new study led by a research team at Ludwig-Maximilians-Universität ...

Cancer created Oct 12, 2012 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Digital mammography improves population-based breast cancer screening

New research from the Netherlands shows that the switch from screen film mammography (SFM) to digital mammography (DM) in large, population-based breast cancer screening programs improves the detection of life-threatening ...

Cancer created Oct 02, 2012 | popularity not rated yet | comments 0

LIFR protein suppresses breast cancer metastasis

A receptor protein suppresses local invasion and metastasis of breast cancer cells, the most lethal aspect of the disease, according to a research team headed by scientists from The University of Texas MD Anderson Cancer ...

Cancer created Sep 25, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

New device may reduce repeat breast cancer surgeries

(HealthDay)—A new device meant to help surgeons determine in the operating room if they have removed all cancerous breast cancer tissue may help reduce repeat surgeries after lumpectomy without compromising ...

Cancer created Sep 12, 2012 | popularity not rated yet | comments 0

New target found for cancers resistant to Iressa and Herceptin

A more-sensitive method to analyze protein interactions has uncovered a new way that cancer cells may use the cell-surface molecule HER3 to drive tumor progression following treatment with HER1 and HER2 inhibitors.

Cancer created Sep 04, 2012 | popularity not rated yet | comments 0 | with audio podcast

Outcomes similar with partial, whole breast irradiation

(HealthDay)—Accelerated partial breast irradiation (APBI) yields five-year clinical outcomes and patterns of failure similar to those achieved with whole breast irradiation (WBI), with excellent three-year ...

Cancer created Aug 24, 2012 | popularity not rated yet | comments 0

LPA1 inhibition induces metastatic dormancy in mouse models of breast cancer

A lysophosphatidic acid receptor 1 (LPAR1) inhibitor, known as Debio-0719, suppresses the development of metastases in mice by inducing cancer cell dormancy, according to a study published August 21 in the Journal of the Na ...

Cancer created Aug 21, 2012 | popularity not rated yet | comments 0