Researchers uncover novel role of BRCA1 in regulating the survival of skin stem cells
Our DNA, which stores our genetic information, is constantly exposed to damage. If not properly repaired, DNA damage can lead to cell death. This, in turn, can lead to tissue exhaustion and ageing, or induce mutations resulting ...
Cancer
Jan 03, 2013 |
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Improving the accuracy of cancer diagnoses: New spectroscopy technique could help doctors better identify breast tumors
Tiny calcium deposits can be a telltale sign of breast cancer. However, in the majority of cases these microcalcifications signal a benign condition. A new diagnostic procedure developed at MIT and Case Western ...
Cancer
Jan 03, 2013 |
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The factor that could influence future breast cancer treatment
Australian scientists have shown in the laboratory how a 'transcription factor' causes breast cancer cells to develop an aggressive subtype that lacks sensitivity to estrogen and does not respond to known anti-estrogen therapies. ...
Cancer
Dec 27, 2012 |
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Understanding cell organization to tackle cancer
Scientists at The University of Manchester have identified how cells know which way up they need to be. The discovery could help in the fight against cancer because in the early stages of the disease the cells become disorganised.
Cancer
Dec 23, 2012 |
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Researchers identify enzyme linked to prostate cancer
Researchers at Mayo Clinic's campus in Florida have identified an enzyme specifically linked to aggressive prostate cancer, and have also developed a compound that inhibits the ability of this molecule to promote the metastatic ...
Cancer
Dec 18, 2012 |
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Changes in progenitor cell population in breast may be overlooked factor in breast cancer
The DNA mutations that accumulate over time as women age are not the sole contributor to the higher frequency of breast cancer in women over 50, Mark LaBarge, PhD, a researcher at Lawrence Berkeley National Laboratory (LBNL) ...
Cancer
Dec 17, 2012 |
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To revert breast cancer cells, give them the squeeze
Researchers at the University of California, Berkeley, and the Lawrence Berkeley National Laboratory have put the squeeze—literally—on malignant mammary cells to guide them back into a normal growth pattern.
Cancer
Dec 17, 2012 |
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Improving the development of new cancer models using an advanced biomedical imaging method
Scientists at the University of Arizona Cancer Center and the Moffitt Cancer Center, led by Dr. Robert Gillies, have demonstrated that an advanced magnetic resonance imaging (MRI) method can non-invasively evaluate the cellular ...
Cancer
Dec 17, 2012 |
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PR+ cells add prognostic value in luminal A breast cancer
(HealthDay)—Semiquantitative immunohistochemical expression of progesterone receptor-positive tumor cells improves prediction of survival within luminal A breast cancers, according to a study published ...
Cancer
Dec 17, 2012 |
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Scientists discover gene linked to breast and ovarian cancer
(Medical Xpress)—A team of researchers led by the Institute of Cancer Research, London, have found that rare mutations in a gene called PPM1D are linked to an increased risk of breast and ovarian cancer. The mutations are ...
Cancer
Dec 17, 2012 |
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The HER2 paradox: HER2-positive stem cells found in HER2-negative breast cancer
A multicenter study led by researchers at UC Davis describes new, paradoxical characteristics of the most common type of breast cancer. The findings shed light on how the disease can evade treatment and could improve diagnosis ...
Cancer
Dec 14, 2012 |
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To fight incurable metastatic breast cancer, resistance must be broken
One of the most frustrating truths about cancer is that even when a treatment works, it often doesn't work for long because cancer cells find ways to resist. However, researchers reporting studies done in mice in the December ...
Cancer
Dec 10, 2012 |
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In vitro study finds digested formula, but not breast milk, is toxic to cells
Free fatty acids created during the digestion of infant formula cause cellular death that may contribute to necrotizing enterocolitis, a severe intestinal condition that is often fatal and occurs most commonly ...
Pediatrics
Dec 10, 2012 |
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Researchers develop novel 3-D culture system for inflammatory breast cancer
Inflammatory breast cancer (IBC) is a very rare and aggressive disease that progresses rapidly and is associated with a very low survival rate. To understand how this type of cancer spreads, it's crucial to characterize the ...
Cancer
Dec 09, 2012 |
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New small molecule inhibitor could be a safe and first-line treatment for metastatic breast cancer
Previous research has shown that a family of genes, proteins and enzymes called the uPA system (for urokinase plasminogen activator) plays an active role in different facets of cancer's biology, including tumor cell invasion, ...
Cancer
Dec 08, 2012 |
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