A novel surface marker helps scientists 'fish out' mammary gland stem cells
Stem cells are different from all other cells in our body because they retain the remarkable genetic plasticity to self-renew indefinitely as well as develop into cell types with more specialized functions. However, this ...
Cancer
Apr 11, 2013 |
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Study finds new drug target for metastatic breast cancer
Research led by Dr. Suresh Alahari, Professor of Biochemistry and Molecular Biology at LSU Health Sciences Center New Orleans, is the first to report that two specific tumor suppressor genes work in concert to inhibit the ...
Cancer
Apr 11, 2013 |
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Roche sales up 5 percent amid rush for Tamiflu, cancer drugs
Swiss drug giant Roche said Thursday that heightened demand for its Tamiflu drug amid a severe flu season, as well as for its cancer medicines had sent its first-quarter sales up five percent, beating analyst expectations.
Medications
Apr 11, 2013 |
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Pfizer breast cancer drug gets breakthrough label
Pfizer Inc. says its experimental pill for advanced, often deadly breast cancer has been designated as a breakthrough therapy by the Food and Drug Administration.
Cancer
Apr 10, 2013 |
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Signature of circulating breast tumor cells that spread to the brain found
Some breast tumor circulating cells in the bloodstream are marked by a constellation of biomarkers that identify them as those destined to seed the brain with a deadly spread of cancer, said researchers led by those at Baylor ...
Cancer
Apr 10, 2013 |
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New approach evaluates effect of physical activity on estrogen metabolism in postmenopausal women
Researchers have generated new insights into the ways in which physical activity affects how much estrogen is broken down and secreted in the urine of postmenopausal women. These findings enhance understanding of the potential ...
Cancer
Apr 10, 2013 |
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Studies show increasing evidence that androgen drives breast cancer
Estrogen and progesterone receptors, and the gene HER2 – these are the big three markers and/or targets in breast cancer. Evidence presented at the AACR Annual Meeting 2013 adds a fourth: androgen receptors.
Cancer
Apr 10, 2013 |
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Probe to detect spread of breast cancer gets distribution boost
A device co-developed by a University of Houston (UH) physicist to detect the spread of breast cancer and allow physicians to better plan intervention is extending its market reach, bringing it another step ...
Cancer
Apr 09, 2013 |
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Quantifying heterogeneity in breast cancer
A variety of mutations may give rise to breast cancer, but scientists generally assume that it starts off with just a few. That's because later-stage breast cancers tend to have more mutations—they are more heterogeneous—than ...
Cancer
Apr 09, 2013 |
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Excess estrogen in pregnancy can silence BRCA1 in daughters, increasing breast cancer risk
Excess estrogen levels during pregnancy can disable, in their daughters, a powerful breast cancer tumor suppressor gene, say researchers at Georgetown Lombardi Comprehensive Cancer Center. They found the DNA repair gene BRCA1 ...
Cancer
Apr 09, 2013 |
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Researchers identify critical metabolic alterations in triple-negative breast cancer cells
Researchers at Fox Chase Cancer Center have identified a host of small molecules critical to metabolism in cells of triple-negative breast cancer—one of the least understood groups of breast cancer. These molecules, called ...
Cancer
Apr 09, 2013 |
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25 percent don't complete recommended breast cancer treatment
One-quarter of women who should take hormone-blocking therapies as part of their breast cancer treatment either do not start or do not complete the five-year course, according to a new study led by University of Michigan ...
Cancer
Apr 09, 2013 |
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Six2 homeoprotein allows breast cancer cells to detach and metastasize
In results presented at the AACR Annual Meeting 2013, researchers from the University of Colorado Cancer Center show that the Six2 homeoprotein, while not involved in primary tumor growth, allows cells to detach from substrate ...
Cancer
Apr 09, 2013 |
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Omega-3 fatty acids more effective at inhibiting growth of triple-negative breast cancer
Researchers from Fox Chase Cancer Center have found that omega-3 fatty acids and their metabolite products slow or stop the proliferation, or growth in the number of cells, of triple-negative breast cancer cells more effectively ...
Cancer
Apr 09, 2013 |
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Patients with BRCA1 mutations, but not BRCA2 mutations, had poorer prognosis compared with noncarriers
Patients with breast cancer who had a BRCA1 mutation had significantly worse overall and recurrence-free survival rates compared with patients without BRCA mutations, but no evidence for a difference in survival was found ...
Cancer
Apr 09, 2013 |
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