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A novel surface marker helps scientists 'fish out' mammary gland stem cells

Stem cells are different from all other cells in our body because they retain the remarkable genetic plasticity to self-renew indefinitely as well as develop into cell types with more specialized functions. However, this ...

Cancer created Apr 11, 2013 | popularity 4 / 5 (1) | comments 0 | with audio podcast

Study finds new drug target for metastatic breast cancer

Research led by Dr. Suresh Alahari, Professor of Biochemistry and Molecular Biology at LSU Health Sciences Center New Orleans, is the first to report that two specific tumor suppressor genes work in concert to inhibit the ...

Cancer created Apr 11, 2013 | popularity 5 / 5 (1) | comments 0

Roche sales up 5 percent amid rush for Tamiflu, cancer drugs

Swiss drug giant Roche said Thursday that heightened demand for its Tamiflu drug amid a severe flu season, as well as for its cancer medicines had sent its first-quarter sales up five percent, beating analyst expectations.

Medications created Apr 11, 2013 | popularity not rated yet | comments 0

Pfizer breast cancer drug gets breakthrough label

Pfizer Inc. says its experimental pill for advanced, often deadly breast cancer has been designated as a breakthrough therapy by the Food and Drug Administration.

Cancer created Apr 10, 2013 | popularity 5 / 5 (1) | comments 0

Signature of circulating breast tumor cells that spread to the brain found

Some breast tumor circulating cells in the bloodstream are marked by a constellation of biomarkers that identify them as those destined to seed the brain with a deadly spread of cancer, said researchers led by those at Baylor ...

Cancer created Apr 10, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast

New approach evaluates effect of physical activity on estrogen metabolism in postmenopausal women

Researchers have generated new insights into the ways in which physical activity affects how much estrogen is broken down and secreted in the urine of postmenopausal women. These findings enhance understanding of the potential ...

Cancer created Apr 10, 2013 | popularity not rated yet | comments 0

Studies show increasing evidence that androgen drives breast cancer

Estrogen and progesterone receptors, and the gene HER2 – these are the big three markers and/or targets in breast cancer. Evidence presented at the AACR Annual Meeting 2013 adds a fourth: androgen receptors.

Cancer created Apr 10, 2013 | popularity 5 / 5 (1) | comments 0

Probe to detect spread of breast cancer gets distribution boost

A device co-developed by a University of Houston (UH) physicist to detect the spread of breast cancer and allow physicians to better plan intervention is extending its market reach, bringing it another step ...

Cancer created Apr 09, 2013 | popularity not rated yet | comments 0

Quantifying heterogeneity in breast cancer

A variety of mutations may give rise to breast cancer, but scientists generally assume that it starts off with just a few. That's because later-stage breast cancers tend to have more mutations—they are more heterogeneous—than ...

Cancer created Apr 09, 2013 | popularity not rated yet | comments 0

Excess estrogen in pregnancy can silence BRCA1 in daughters, increasing breast cancer risk

Excess estrogen levels during pregnancy can disable, in their daughters, a powerful breast cancer tumor suppressor gene, say researchers at Georgetown Lombardi Comprehensive Cancer Center. They found the DNA repair gene BRCA1 ...

Cancer created Apr 09, 2013 | popularity not rated yet | comments 0

Researchers identify critical metabolic alterations in triple-negative breast cancer cells

Researchers at Fox Chase Cancer Center have identified a host of small molecules critical to metabolism in cells of triple-negative breast cancer—one of the least understood groups of breast cancer. These molecules, called ...

Cancer created Apr 09, 2013 | popularity not rated yet | comments 0

25 percent don't complete recommended breast cancer treatment

One-quarter of women who should take hormone-blocking therapies as part of their breast cancer treatment either do not start or do not complete the five-year course, according to a new study led by University of Michigan ...

Cancer created Apr 09, 2013 | popularity not rated yet | comments 0

Six2 homeoprotein allows breast cancer cells to detach and metastasize

In results presented at the AACR Annual Meeting 2013, researchers from the University of Colorado Cancer Center show that the Six2 homeoprotein, while not involved in primary tumor growth, allows cells to detach from substrate ...

Cancer created Apr 09, 2013 | popularity not rated yet | comments 0

Omega-3 fatty acids more effective at inhibiting growth of triple-negative breast cancer

Researchers from Fox Chase Cancer Center have found that omega-3 fatty acids and their metabolite products slow or stop the proliferation, or growth in the number of cells, of triple-negative breast cancer cells more effectively ...

Cancer created Apr 09, 2013 | popularity 4 / 5 (1) | comments 0

Patients with BRCA1 mutations, but not BRCA2 mutations, had poorer prognosis compared with noncarriers

Patients with breast cancer who had a BRCA1 mutation had significantly worse overall and recurrence-free survival rates compared with patients without BRCA mutations, but no evidence for a difference in survival was found ...

Cancer created Apr 09, 2013 | popularity 5 / 5 (1) | comments 0