News tagged with calcineurin

Schizophrenia linked to abnormal brain waves

Schizophrenia patients usually suffer from a breakdown of organized thought, often accompanied by delusions or hallucinations. For the first time, MIT neuroscientists have observed the neural activity that ...

Oct 16, 2013
popularity 4.9 / 5 (15) | comments 6 | with audio podcast

Lifetime of transplanted kidneys can be prolonged

The drug Belatacept, which the Medical University of Vienna – represented by Ferdinand Mühlbacher, Head of the University Department of Surgery and the immunologist Thomas Wekerle – was greatly involved ...

Sep 10, 2013
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Drug class linked to worse outcomes after transplant

(HealthDay)—Kidney transplant patients who receive mammalian target of rapamycin (mTOR) inhibitors after transplant have a greater probability of death or transplant failure than patients receiving calcineurin ...

Oct 14, 2012
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Immunosuppressant switch cuts skin cancer post-transplant

(HealthDay) -- In kidney-transplant patients with at least one cutaneous squamous-cell carcinoma, switching immunosuppressants (from calcineurin inhibitors to sirolimus) is associated with increased skin cancer-free ...

Jul 26, 2012
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Mechanistic insights into Old English plants

Often lacking in natural product drug discovery are ‘mechanistic insights’; that is, insights into the events at the molecular level that are behind any effects that plant compounds have on cells ...

Jul 10, 2012
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Time to stop giving toxic drugs to kidney transplant patients?

Patients who receive kidney transplants must take lifelong medications that, while preventing organ rejection, can also compromise other aspects of health. Immunosuppresive drugs called calcineurin inhibitors protect transplanted ...

Sep 22, 2011
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