Scientists at VCU Massey Cancer Center have uncovered a previously unrecognized relationship between two sets of proteins that operate in tandem to fend off the growth of pancreatic cancer. The findings could provide pivotal ...
Mar 1, 2023
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Mutations of the gene encoding dystrophins have long been known to cause the debilitating muscle-wasting disease Duchenne muscular dystrophy (DMD), which affects one in every 5,000 children born, mostly boys. People with ...
Feb 27, 2023
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FGFR3-TACC3 represents an oncogenic fusion protein frequently identified in glioblastoma, lung cancer, bladder cancer, oral cancer, head and neck squamous cell carcinoma, gallbladder cancer, and cervical cancer. Various exon ...
Feb 23, 2023
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Cancer biologists are yet to understand the mechanisms and cellular hierarchy leading to the developmental arrest in rhabdomyosarcoma (RMS)—a group of pediatric cancers, which remain enigmatic.
Breakthrough SARS-CoV-2 infections following vaccination against COVID-19 are of international concern and patients with cancer are highly vulnerable and susceptible to poor outcomes.
Feb 17, 2023
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A recent study conducted as part of the ORCHESTRA project has shed new light on the treatment of COVID-19 infections with mAbs. Published in the Journal of Clinical Investigation, the research reveals that patients treated ...
Feb 17, 2023
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An approved drug for chronic constipation also relieves the pain associated with that condition. New research by Scott Waldman, MD, Ph.D., chair of pharmacology, physiology and cancer biology at Jefferson, demonstrates that ...
Feb 17, 2023
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Epigenetic age, a robust marker of biological aging, has been associated with obesity, low-grade inflammation and metabolic diseases. However, few studies have examined associations between different epigenetic age measures ...
Feb 16, 2023
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It is now widely understood that cancer is a disease of acquired defects in genes and gene function. An article published Feb. 9 in Science, and authored by Andrew Feinberg, M.D., of the Johns Hopkins Kimmel Cancer Center ...
Feb 10, 2023
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More than 10% of older adults develop somatic (non-inherited) mutations in blood stem cells that can trigger explosive, clonal expansions of abnormal cells, increasing the risk for blood cancer and cardiovascular disease.
Feb 8, 2023
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