Cancer drugs often don't behave as expected in clinical trials. A study published Oct. 11 in the journal Cell Chemical Biology explores why drugs under development are unlikely to work due to insufficient genetic analysis.
Oct 25, 2023
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A research team from the UC Davis Comprehensive Cancer Center has identified a crucial epitope (a protein section that can activate the larger protein) on the CD95 receptor that can cause cells to die. This new ability to ...
Oct 24, 2023
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A study in human cell lines reveals cancer cells can activate a force-generating mechanism to survive a cancer therapy.
Oct 24, 2023
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Cedars-Sinai Cancer investigators have identified two promising new treatment options for men with recurrent prostate cancer—both of which helped patients live longer without their disease progressing than the current standard ...
Oct 18, 2023
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Polygenic risk scores, which estimate a person's disease risk based on thousands or millions of common genetic variants, perform poorly in screening and prediction of common diseases such as heart disease, according to a ...
Oct 17, 2023
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The lung is one of the tissues most sensitive to radiation in the human body. People exposed to high radiation doses following nuclear incidents develop radiation-induced lung injury (RILI), which affects the function of ...
Oct 17, 2023
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Targeted cancer drugs are widely used because of their ability to inhibit specific proteins involved in cancer development with fewer side effects compared to chemotherapy drugs. But targeted therapies can often inhibit other ...
Oct 16, 2023
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Removing a patient's tumor while sparing healthy tissue requires exquisite precision, but often surgeons must rely on their eyes and hands to determine where to cut.
Oct 16, 2023
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Cancer research has long focused on targeting the genetic mutations that drive tumors. Many of these genetic changes affect genes that allow mutated cells to replicate out of control. While developing drugs to target these ...
Oct 16, 2023
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Cutaneous squamous cell carcinoma is the second most common type of skin cancer in the United States, impacting approximately 700,000 people each year. While medications exist to prevent the development of disease, they are ...
Oct 11, 2023
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