Immune system T cells that should be able to kill cancer cells become dysfunctional or "exhausted" within hours of encountering a tumor, according to a study reported Aug. 3 in Nature Immunology.
Aug 3, 2023
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Scientists at Stanford University have found a way to induce cell death in cancer cells with a method that could be effective in around 50% of cancers. In a paper, "Rewiring cancer drivers to activate apoptosis," published ...
Researchers from A*STAR's Institute of Molecular and Cell Biology (IMCB) and National Cancer Centre Singapore (NCCS) have discovered how the loss of a gene, PBRM1, can lead to the development of kidney cancer. The work is ...
Jul 28, 2023
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New research in colorectal cancers directed by investigators at the Johns Hopkins Kimmel Cancer Center suggests that expression of transcription factors—proteins that help turn specific genes on or off by binding to nearby ...
Jul 27, 2023
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Rhabdomyosarcoma, a malignant tumor, is one of the most common soft tissue tumors occurring during childhood. The tumors are associated with skeletal muscle and can emerge anywhere in the body. Consequently, the clinical ...
Jul 26, 2023
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A surprising finding from USC reveals key details about how cancer cells metastasize and suggests new therapeutic approaches for halting their spread.
Jul 24, 2023
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While pembrolizumab is an approved treatment for patients with stage III non-small cell lung cancer (NSCLC), only some patients respond to this therapy. Treatment failure, researchers say, is often caused by differences in ...
Jul 13, 2023
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An atlas that catalogs gene activity and the levels of small molecules called metabolites in tumor samples offers a new way of identifying the deep mechanisms of cancer, according to researchers at Weill Cornell Medicine ...
Jun 29, 2023
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Mutations in the KRAS gene are the major driver of pancreatic cancer. The resulting protein controls multiple signaling pathways involved in cell growth and survival. In cancer, the gene is mutated to be permanently "on," ...
Jun 29, 2023
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The gastric corpus, which is a major component of the glandular stomach, is composed of parietal, chief, pit, and neck cells. Each of these specialized epithelial cells play an important role in digestion, and they are continuously ...
Jun 29, 2023
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