Hundreds of alterations and potential drug targets to starve cancer tumors identified
A massive study analyzing gene expression data from 22 tumor types has identified multiple metabolic expression changes associated with cancer. The analysis, conducted by researchers at Columbia University Medical Center, ...
Cancer
Apr 21, 2013 |
5 / 5 (4) |
0
|
Patenting genes: Justices tackle big health issue (Update 2)
The Supreme Court seemed worried Monday about the idea of companies patenting human genes in a case that could profoundly reshape the multibillion-dollar biomedical industry and U.S. research in the fight ...
Genetics
Apr 15, 2013 |
5 / 5 (2) |
1
Are human genes patentable?
(Medical Xpress)—On April 15, the Supreme Court will hear oral argument in Association for Molecular Pathology v. Myriad Genetics, a case that could answer the question, "Under what conditions, if any, ...
Genetics
Apr 11, 2013 |
4.3 / 5 (6) |
16
|
Scientists find new gene markers for cancer risk
A huge international effort involving more than 100 institutions and genetic tests on 200,000 people has uncovered dozens of signposts in DNA that can help reveal further a person's risk for breast, ovarian ...
Genetics
Mar 27, 2013 |
5 / 5 (4) |
1
First evidence that obesity gene is risk factor for melanoma
The gene most strongly linked to obesity and overeating may also increase the risk of malignant melanoma – the most deadly skin cancer, reveals research published in Nature Genetics.
Genetics
Mar 04, 2013 |
5 / 5 (1) |
0
|
New mutations driving malignant melanoma discovered
Two new mutations that collectively occur in 71 percent of malignant melanoma tumors have been discovered in what scientists call the "dark matter" of the cancer genome, where cancer-related mutations haven't ...
Cancer
Jan 24, 2013 |
not rated yet |
0
|
Tumors evolve rapidly in a childhood cancer, leaving fewer obvious tumor targets
An extensive genomic study of the childhood cancer neuroblastoma reinforces the challenges in treating the most aggressive forms of this disease. Contrary to expectations, the scientists found relatively few recurrent gene ...
Genetics
Jan 20, 2013 |
5 / 5 (2) |
0
|
Study finds new genetic defects in high-risk childhood leukemia subtypes with chromosomal loss
Research led by St. Jude Children's Research Hospital scientists has identified a possible lead in treatment of two childhood leukemia subtypes known for their dramatic loss of chromosomes and poor treatment outcomes.
Genetics
Jan 20, 2013 |
not rated yet |
0
|
Cancer suppressor gene links metabolism with cellular aging
The tumor suppressor protein p53 is an attractive target for drug developers. But this path has so far proven difficult, as most p53 regulatory proteins operate via protein-protein interactions, which make for poor drug targets, ...
Cancer
Jan 13, 2013 |
3.7 / 5 (3) |
0
|
Researchers find new culprit in castration-resistant prostate cancer
Scientists at Dana-Farber Cancer Institute have discovered a molecular switch that enables advanced prostate cancers to spread without stimulation by male hormones, which normally are needed to spur the cancer's growth. They ...
Cancer
Dec 13, 2012 |
not rated yet |
0
|
Researchers use microRNAs to induce regeneration of heart tissue
(Medical Xpress)—A research team working at Italy's International Centre for Genetic Engineering and Biotechnology has succeeded in causing heart tissue to regenerate by introducing two microRNAs into damaged mice hearts. ...
Medical research
Dec 06, 2012 |
5 / 5 (2) |
1
|
MicroRNAs can convert normal cells into cancer promoters
Unraveling the mechanism that ovarian cancer cells use to change normal cells around them into cells that promote tumor growth has identified several new targets for treatment of this deadly disease.
Cancer
Nov 21, 2012 |
5 / 5 (2) |
0
|
First gene therapy study in human salivary gland shows promise
Gene therapy can be performed safely in the human salivary gland, according to scientists at the National Institute of Dental and Craniofacial Research (NIDCR), part of the National Institutes of Health.
Cancer
Nov 05, 2012 |
5 / 5 (2) |
0
|
Genetic switch shuts down lung cancer tumors in mice
Yale researchers manipulated a tiny genetic switch and halted growth of aggressive lung cancer tumors in mice and even prevented tumors from forming.
Cancer
Oct 25, 2012 |
4.6 / 5 (7) |
0
|
After three decades of searching, scientists find cellular targets of Hepatitis B virus
A University of Colorado Boulder-led team has discovered two prime targets of the Hepatitis B virus in liver cells, findings that could lead to treatment of liver disease in some of the 400 million people worldwide currently ...
Diseases, Conditions, Syndromes
Oct 22, 2012 |
3.7 / 5 (3) |
0
|
