Oncology & Cancer

Scientists find surprising impact of junk DNA and RNA in cancer

"Human satellite II," an exceptionally high-copy but unexplored sequence of the human genome thought of as "junk DNA," has a surprising ability to impact master regulators of our genome, and it goes awry in 50 percent of ...

Medical research

The First Cell: Jump-starting the global cancer revolution

"The First Cell" is the title of a revolutionary book written in 2019 by oncologist Azra Raza from the Columbia University Medical Center. In it, she calls for a radical shift in cancer funding away from its current predominant ...

Oncology & Cancer

Massive genome havoc in breast cancer is revealed

In cancer cells, genetic errors wreak havoc. Misspelled genes, as well as structural variations—larger-scale rearrangements of DNA that can encompass large chunks of chromosomes—disturb carefully balanced mechanisms that ...

Genetics

When and how mutant clones expand in normal endometrium

Monthly menstruation is a biological phenomenon in women of reproductive age that involves morphological and functional changes in the uterine endometrium followed by uterine lining shedding. The endometrial layer can regenerate ...

Oncology & Cancer

Ancient viruses could help kill cancers

DNA "echoes" of viruses that infected our ancestors millions of years ago could help the immune system to identify and kill cancer cells, according to new research from Crick scientists.

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