New model helps identify mutations that drive cancer
Cancer cells can have thousands of mutations in their DNA. However, only a handful of those actually drive the progression of cancer; the rest are just along for the ride.
Jun 20, 2022
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Cancer cells can have thousands of mutations in their DNA. However, only a handful of those actually drive the progression of cancer; the rest are just along for the ride.
Jun 20, 2022
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The first-ever published whole-genome sequences of not just one, but two supercentenarians, aged more than 114 years, reveal that both unusual and common genetic phenomena contribute to the genetic background of extreme human ...
Jan 3, 2012
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Are the greatest advances made in science based on serendipity? University of Minnesota Professor of Genetics and Cell Biology Perry Hackett thinks so.
Sep 28, 2018
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A person's risk of developing cancer is affected by genetic variations in regions of DNA that don't code for proteins, previously dismissed as 'junk DNA', according to new research published in the British Journal of Cancer ...
Dec 6, 2019
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Growing insights about a significant, yet poorly understood, part of the genome - the "dark matter of DNA"—have fundamentally changed the way scientists approach the study of diseases. The human genome contains about 20,000 ...
Oct 12, 2015
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St. Jude Children's Research Hospital has re-defined the gold standard for diagnostic testing of childhood cancer patients in the precision-medicine era and has implemented the testing for new cancer patients. The findings ...
Oct 12, 2018
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UT Southwestern Medical Center cancer researchers have demonstrated that whole-genome sequencing can be used to identify patients' risk for hereditary cancer, which can potentially lead to improvements in cancer prevention, ...
Dec 23, 2014
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The Griffith University scientists used CRISPR-Cas9 to successfully target and treat cervical cancer tumours in vivo (via injection into live and tumour-bearing mice) using "stealth" nanoparticles.
Oct 10, 2019
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Four stranded DNA structures—known as G-quadruplexes—have been shown to play a role in certain types of breast cancer for the first time, providing a potential new target for personalised medicine, say scientists at the ...
Aug 3, 2020
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In an amazing twist of fate, the aggressive cervical cancer tumor that killed Henrietta Lacks, a 31-year old African American mother, became an essential tool that helped the biomedical field flourish in the 20th century. ...
Jun 1, 2022
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